Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1179c

Experiment: 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1178 and Rv1179c are separated by 27 nucleotidesRv1179c and Rv1180 are separated by 425 nucleotides Rv1178: Rv1178 - Probable aminotransferase, at 1,309,364 to 1,310,452 Rv1178 Rv1179c: Rv1179c - Unknown protein, at 1,310,480 to 1,313,299 Rv1179c Rv1180: Rv1180 - Probable polyketide beta-ketoacyl synthase Pks3, at 1,313,725 to 1,315,191 Rv1180 Position (kb) 1310 1311 1312 1313 1314Strain fitness (log2 ratio) -1 0 1 2 3at 1309.719 kb on - strand, within Rv1178at 1309.815 kb on - strand, within Rv1178at 1309.966 kb on - strand, within Rv1178at 1310.094 kb on + strand, within Rv1178at 1310.095 kb on - strand, within Rv1178at 1310.147 kb on - strand, within Rv1178at 1310.280 kb on + strand, within Rv1178at 1310.281 kb on - strand, within Rv1178at 1310.801 kb on + strand, within Rv1179cat 1310.801 kb on + strand, within Rv1179cat 1310.802 kb on - strand, within Rv1179cat 1311.280 kb on - strand, within Rv1179cat 1311.447 kb on + strand, within Rv1179cat 1311.448 kb on - strand, within Rv1179cat 1311.481 kb on - strand, within Rv1179cat 1311.665 kb on + strand, within Rv1179cat 1311.665 kb on + strand, within Rv1179cat 1311.665 kb on + strand, within Rv1179cat 1311.666 kb on - strand, within Rv1179cat 1311.666 kb on - strand, within Rv1179cat 1311.715 kb on - strand, within Rv1179cat 1311.715 kb on - strand, within Rv1179cat 1311.715 kb on - strand, within Rv1179cat 1311.739 kb on + strand, within Rv1179cat 1311.739 kb on + strand, within Rv1179cat 1311.739 kb on + strand, within Rv1179cat 1311.740 kb on - strand, within Rv1179cat 1311.740 kb on - strand, within Rv1179cat 1311.781 kb on + strand, within Rv1179cat 1311.781 kb on + strand, within Rv1179cat 1312.158 kb on - strand, within Rv1179cat 1312.277 kb on + strand, within Rv1179cat 1312.278 kb on - strand, within Rv1179cat 1312.278 kb on - strand, within Rv1179cat 1312.590 kb on + strand, within Rv1179cat 1312.590 kb on + strand, within Rv1179cat 1312.590 kb on + strand, within Rv1179cat 1312.792 kb on + strand, within Rv1179cat 1312.792 kb on + strand, within Rv1179cat 1312.792 kb on + strand, within Rv1179cat 1312.793 kb on - strand, within Rv1179cat 1312.793 kb on - strand, within Rv1179cat 1312.797 kb on - strand, within Rv1179cat 1312.839 kb on - strand, within Rv1179cat 1312.975 kb on - strand, within Rv1179cat 1313.247 kb on - strandat 1313.457 kb on + strandat 1313.557 kb on + strandat 1313.587 kb on - strandat 1313.627 kb on + strandat 1313.675 kb on - strandat 1313.879 kb on - strand, within Rv1180at 1314.211 kb on + strand, within Rv1180

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM
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1,309,719 - Rv1178 0.33 +0.1
1,309,815 - Rv1178 0.41 +0.5
1,309,966 - Rv1178 0.55 +0.3
1,310,094 + Rv1178 0.67 -1.1
1,310,095 - Rv1178 0.67 -0.1
1,310,147 - Rv1178 0.72 -1.7
1,310,280 + Rv1178 0.84 +0.1
1,310,281 - Rv1178 0.84 +1.7
1,310,801 + Rv1179c 0.11 +0.7
1,310,801 + Rv1179c 0.11 +0.8
1,310,802 - Rv1179c 0.11 -0.1
1,311,280 - Rv1179c 0.28 +0.2
1,311,447 + Rv1179c 0.34 +0.6
1,311,448 - Rv1179c 0.34 +0.3
1,311,481 - Rv1179c 0.35 +0.0
1,311,665 + Rv1179c 0.42 -0.5
1,311,665 + Rv1179c 0.42 +0.7
1,311,665 + Rv1179c 0.42 +2.0
1,311,666 - Rv1179c 0.42 +0.2
1,311,666 - Rv1179c 0.42 -0.1
1,311,715 - Rv1179c 0.44 +1.9
1,311,715 - Rv1179c 0.44 +0.1
1,311,715 - Rv1179c 0.44 -0.5
1,311,739 + Rv1179c 0.45 -0.1
1,311,739 + Rv1179c 0.45 +0.6
1,311,739 + Rv1179c 0.45 -0.3
1,311,740 - Rv1179c 0.45 +0.4
1,311,740 - Rv1179c 0.45 -0.5
1,311,781 + Rv1179c 0.46 -1.1
1,311,781 + Rv1179c 0.46 +0.5
1,312,158 - Rv1179c 0.60 +0.0
1,312,277 + Rv1179c 0.64 -0.3
1,312,278 - Rv1179c 0.64 +2.9
1,312,278 - Rv1179c 0.64 +0.8
1,312,590 + Rv1179c 0.75 -0.1
1,312,590 + Rv1179c 0.75 +0.9
1,312,590 + Rv1179c 0.75 -0.0
1,312,792 + Rv1179c 0.82 -1.2
1,312,792 + Rv1179c 0.82 -0.7
1,312,792 + Rv1179c 0.82 +0.2
1,312,793 - Rv1179c 0.82 -0.7
1,312,793 - Rv1179c 0.82 +1.0
1,312,797 - Rv1179c 0.82 -0.3
1,312,839 - Rv1179c 0.84 -1.1
1,312,975 - Rv1179c 0.88 -0.5
1,313,247 - +0.5
1,313,457 + -0.6
1,313,557 + +1.9
1,313,587 - +2.3
1,313,627 + +0.6
1,313,675 - +0.5
1,313,879 - Rv1180 0.10 +0.2
1,314,211 + Rv1180 0.33 -0.8

Or see this region's nucleotide sequence