Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0229c

Experiment: 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0228 and Rv0229c are separated by 27 nucleotidesRv0229c and Rv0230c overlap by 4 nucleotides Rv0228: Rv0228 - Probable integral membrane acyltransferase, at 273,055 to 274,278 Rv0228 Rv0229c: Rv0229c - Possible conserved membrane protein with PIN domain, at 274,306 to 274,986 Rv0229c Rv0230c: Rv0230c - Probable phosphotriesterase Php (parathion hydrolase) (PTE) (aryldialkylphosphatase) (paraoxonase) (a-esterase) (aryltriphosphatase) (paraoxon hydrolase), at 274,983 to 275,963 Rv0230c Position (kb) 274 275Strain fitness (log2 ratio) -3 -2 -1 0 1 2 3at 274.307 kb on + strandat 274.390 kb on + strand, within Rv0229cat 274.391 kb on - strand, within Rv0229cat 274.461 kb on + strand, within Rv0229cat 274.474 kb on + strand, within Rv0229cat 274.607 kb on - strand, within Rv0229cat 274.607 kb on - strand, within Rv0229cat 274.706 kb on + strand, within Rv0229cat 274.707 kb on - strand, within Rv0229cat 274.707 kb on - strand, within Rv0229cat 274.854 kb on - strand, within Rv0229cat 274.854 kb on - strand, within Rv0229cat 274.919 kb on - strandat 274.939 kb on + strandat 275.108 kb on - strand, within Rv0230cat 275.162 kb on - strand, within Rv0230cat 275.182 kb on - strand, within Rv0230cat 275.287 kb on + strand, within Rv0230cat 275.287 kb on + strand, within Rv0230cat 275.288 kb on - strand, within Rv0230cat 275.317 kb on + strand, within Rv0230cat 275.318 kb on - strand, within Rv0230cat 275.638 kb on + strand, within Rv0230cat 275.638 kb on + strand, within Rv0230cat 275.639 kb on - strand, within Rv0230cat 275.647 kb on + strand, within Rv0230cat 275.665 kb on + strand, within Rv0230cat 275.666 kb on - strand, within Rv0230cat 275.666 kb on - strand, within Rv0230cat 275.671 kb on + strand, within Rv0230cat 275.671 kb on + strand, within Rv0230cat 275.671 kb on + strand, within Rv0230cat 275.737 kb on + strand, within Rv0230cat 275.738 kb on - strand, within Rv0230cat 275.738 kb on - strand, within Rv0230cat 275.948 kb on + strandat 275.948 kb on + strandat 275.952 kb on + strandat 275.952 kb on + strandat 275.952 kb on + strandat 275.952 kb on + strandat 275.953 kb on - strandat 275.975 kb on + strandat 275.975 kb on + strandat 275.976 kb on - strandat 275.976 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM
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274,307 + -1.1
274,390 + Rv0229c 0.12 -0.4
274,391 - Rv0229c 0.12 -0.4
274,461 + Rv0229c 0.23 +0.6
274,474 + Rv0229c 0.25 -0.9
274,607 - Rv0229c 0.44 -0.1
274,607 - Rv0229c 0.44 -1.7
274,706 + Rv0229c 0.59 -0.7
274,707 - Rv0229c 0.59 -1.1
274,707 - Rv0229c 0.59 +1.9
274,854 - Rv0229c 0.80 +2.9
274,854 - Rv0229c 0.80 -1.2
274,919 - -0.3
274,939 + -0.3
275,108 - Rv0230c 0.13 -0.6
275,162 - Rv0230c 0.18 -0.8
275,182 - Rv0230c 0.20 -0.4
275,287 + Rv0230c 0.31 +0.8
275,287 + Rv0230c 0.31 +0.3
275,288 - Rv0230c 0.31 -0.3
275,317 + Rv0230c 0.34 -0.1
275,318 - Rv0230c 0.34 -0.1
275,638 + Rv0230c 0.67 -0.1
275,638 + Rv0230c 0.67 -0.3
275,639 - Rv0230c 0.67 -1.2
275,647 + Rv0230c 0.68 +0.1
275,665 + Rv0230c 0.70 -0.1
275,666 - Rv0230c 0.70 -0.6
275,666 - Rv0230c 0.70 +0.2
275,671 + Rv0230c 0.70 +0.0
275,671 + Rv0230c 0.70 +0.0
275,671 + Rv0230c 0.70 -1.1
275,737 + Rv0230c 0.77 -0.9
275,738 - Rv0230c 0.77 -0.7
275,738 - Rv0230c 0.77 -0.0
275,948 + -0.4
275,948 + -0.2
275,952 + -0.7
275,952 + -0.2
275,952 + -0.4
275,952 + -0.4
275,953 - +0.3
275,975 + -0.1
275,975 + -0.5
275,976 - -1.0
275,976 - -2.8

Or see this region's nucleotide sequence