Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3636

Experiment: 7H9 with Thioridazine 0.028 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3635 and Rv3636 are separated by 342 nucleotidesRv3636 and Rv3637 are separated by 384 nucleotidesRv3637 and Rv3638 overlap by 1 nucleotides Rv3635: Rv3635 - Probable conserved transmembrane protein, at 4,073,634 to 4,075,409 Rv3635 Rv3636: Rv3636 - Possible transposase, at 4,075,752 to 4,076,099 Rv3636 Rv3637: Rv3637 - Possible transposase, at 4,076,484 to 4,076,984 Rv3637 Rv3638: Rv3638 - Possible transposase, at 4,076,984 to 4,077,730 Rv3638 Position (kb) 4075 4076 4077Strain fitness (log2 ratio) -2 -1 0 1at 4075.494 kb on - strandat 4075.646 kb on + strandat 4075.646 kb on + strandat 4075.655 kb on + strandat 4075.655 kb on + strandat 4075.731 kb on + strandat 4076.056 kb on - strand, within Rv3636at 4076.086 kb on + strandat 4076.087 kb on - strandat 4076.087 kb on - strandat 4076.257 kb on + strandat 4076.258 kb on - strandat 4076.258 kb on - strandat 4076.523 kb on - strandat 4076.689 kb on - strand, within Rv3637at 4076.689 kb on - strand, within Rv3637at 4076.946 kb on + strandat 4076.946 kb on + strandat 4076.947 kb on - strandat 4076.947 kb on - strandat 4076.947 kb on - strandat 4076.947 kb on - strandat 4076.947 kb on - strandat 4077.035 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Thioridazine 0.028 mM
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4,075,494 - -0.9
4,075,646 + +0.5
4,075,646 + -0.3
4,075,655 + -0.3
4,075,655 + -0.1
4,075,731 + -0.1
4,076,056 - Rv3636 0.87 -0.6
4,076,086 + -0.1
4,076,087 - -0.4
4,076,087 - -0.2
4,076,257 + -0.8
4,076,258 - +1.7
4,076,258 - -0.7
4,076,523 - -0.0
4,076,689 - Rv3637 0.41 -0.0
4,076,689 - Rv3637 0.41 +0.3
4,076,946 + -0.8
4,076,946 + +0.2
4,076,947 - -2.0
4,076,947 - +0.7
4,076,947 - +0.6
4,076,947 - -2.7
4,076,947 - -0.3
4,077,035 + +0.1

Or see this region's nucleotide sequence