Experiment: 7H9 with Thioridazine 0.028 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0444c and Rv0445c are separated by 43 nucleotides Rv0445c and Rv0446c are separated by 48 nucleotides Rv0446c and Rv0447c are separated by 8 nucleotides
Rv0444c: Rv0444c - Anti-sigma factor RskA (regulator of sigma K), at 533,091 to 533,789
Rv0444c
Rv0445c: Rv0445c - Alternative RNA polymerase sigma factor SigK, at 533,833 to 534,396
Rv0445c
Rv0446c: Rv0446c - Possible conserved transmembrane protein, at 534,445 to 535,215
Rv0446c
Rv0447c: Rv0447c - Probable cyclopropane-fatty-acyl-phospholipid synthase UfaA1 (cyclopropane fatty acid synthase) (CFA synthase), at 535,224 to 536,507
Rv0447c
Position (kb) 534
535
536 Strain fitness (log2 ratio) -2
-1
0
1
2 at 533.522 kb on + strand, within Rv0444c at 533.743 kb on + strand at 533.744 kb on - strand at 533.751 kb on - strand at 533.933 kb on + strand, within Rv0445c at 533.933 kb on + strand, within Rv0445c at 533.934 kb on - strand, within Rv0445c at 533.934 kb on - strand, within Rv0445c at 533.951 kb on + strand, within Rv0445c at 533.951 kb on + strand, within Rv0445c at 533.952 kb on - strand, within Rv0445c at 533.952 kb on - strand, within Rv0445c at 533.952 kb on - strand, within Rv0445c at 533.952 kb on - strand, within Rv0445c at 534.084 kb on - strand, within Rv0445c at 534.248 kb on + strand, within Rv0445c at 534.285 kb on - strand, within Rv0445c at 534.285 kb on - strand, within Rv0445c at 534.309 kb on - strand, within Rv0445c at 534.483 kb on - strand at 534.530 kb on + strand, within Rv0446c at 534.668 kb on + strand, within Rv0446c at 534.669 kb on - strand, within Rv0446c at 534.742 kb on + strand, within Rv0446c at 534.898 kb on + strand, within Rv0446c at 534.992 kb on + strand, within Rv0446c at 534.992 kb on + strand, within Rv0446c at 534.992 kb on + strand, within Rv0446c at 535.036 kb on + strand, within Rv0446c at 535.037 kb on - strand, within Rv0446c at 535.039 kb on + strand, within Rv0446c at 535.118 kb on - strand, within Rv0446c at 535.136 kb on + strand, within Rv0446c at 535.136 kb on + strand, within Rv0446c at 535.136 kb on + strand, within Rv0446c at 535.258 kb on + strand at 535.259 kb on - strand at 535.307 kb on - strand at 535.344 kb on + strand at 535.373 kb on + strand, within Rv0447c at 535.374 kb on - strand, within Rv0447c at 535.409 kb on - strand, within Rv0447c at 535.513 kb on + strand, within Rv0447c at 535.514 kb on - strand, within Rv0447c at 535.514 kb on - strand, within Rv0447c at 535.618 kb on - strand, within Rv0447c at 535.681 kb on - strand, within Rv0447c at 535.681 kb on - strand, within Rv0447c at 535.690 kb on + strand, within Rv0447c at 535.691 kb on - strand, within Rv0447c at 535.999 kb on + strand, within Rv0447c at 536.050 kb on + strand, within Rv0447c at 536.061 kb on + strand, within Rv0447c at 536.061 kb on + strand, within Rv0447c at 536.062 kb on - strand, within Rv0447c at 536.062 kb on - strand, within Rv0447c at 536.062 kb on - strand, within Rv0447c at 536.062 kb on - strand, within Rv0447c at 536.062 kb on - strand, within Rv0447c at 536.062 kb on - strand, within Rv0447c at 536.062 kb on - strand, within Rv0447c at 536.064 kb on - strand, within Rv0447c at 536.064 kb on - strand, within Rv0447c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Thioridazine 0.028 mM remove 533,522 + Rv0444c 0.62 +0.3 533,743 + -0.9 533,744 - -0.6 533,751 - -0.2 533,933 + Rv0445c 0.18 -0.3 533,933 + Rv0445c 0.18 -0.2 533,934 - Rv0445c 0.18 -0.9 533,934 - Rv0445c 0.18 +0.1 533,951 + Rv0445c 0.21 +0.8 533,951 + Rv0445c 0.21 -0.3 533,952 - Rv0445c 0.21 -0.2 533,952 - Rv0445c 0.21 +0.8 533,952 - Rv0445c 0.21 -0.0 533,952 - Rv0445c 0.21 -0.5 534,084 - Rv0445c 0.45 -0.3 534,248 + Rv0445c 0.74 -0.3 534,285 - Rv0445c 0.80 -0.9 534,285 - Rv0445c 0.80 -0.7 534,309 - Rv0445c 0.84 +0.0 534,483 - -0.1 534,530 + Rv0446c 0.11 -1.2 534,668 + Rv0446c 0.29 +0.0 534,669 - Rv0446c 0.29 +0.3 534,742 + Rv0446c 0.39 -0.2 534,898 + Rv0446c 0.59 -0.6 534,992 + Rv0446c 0.71 -0.7 534,992 + Rv0446c 0.71 -0.3 534,992 + Rv0446c 0.71 +0.7 535,036 + Rv0446c 0.77 -0.1 535,037 - Rv0446c 0.77 -0.0 535,039 + Rv0446c 0.77 -2.2 535,118 - Rv0446c 0.87 -0.8 535,136 + Rv0446c 0.90 -0.4 535,136 + Rv0446c 0.90 -0.6 535,136 + Rv0446c 0.90 -1.6 535,258 + +2.7 535,259 - +0.2 535,307 - -1.9 535,344 + +0.2 535,373 + Rv0447c 0.12 +1.7 535,374 - Rv0447c 0.12 +0.1 535,409 - Rv0447c 0.14 +0.4 535,513 + Rv0447c 0.23 -0.4 535,514 - Rv0447c 0.23 +0.1 535,514 - Rv0447c 0.23 -1.1 535,618 - Rv0447c 0.31 +0.2 535,681 - Rv0447c 0.36 +0.3 535,681 - Rv0447c 0.36 -0.6 535,690 + Rv0447c 0.36 -0.3 535,691 - Rv0447c 0.36 +1.1 535,999 + Rv0447c 0.60 -1.9 536,050 + Rv0447c 0.64 -0.3 536,061 + Rv0447c 0.65 +1.2 536,061 + Rv0447c 0.65 -0.3 536,062 - Rv0447c 0.65 -0.3 536,062 - Rv0447c 0.65 +0.4 536,062 - Rv0447c 0.65 -1.1 536,062 - Rv0447c 0.65 -0.1 536,062 - Rv0447c 0.65 -0.7 536,062 - Rv0447c 0.65 +1.1 536,062 - Rv0447c 0.65 -0.9 536,064 - Rv0447c 0.65 +0.8 536,064 - Rv0447c 0.65 -0.6
Or see this region's nucleotide sequence