Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3071

Experiment: 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3068c and Rv3069 are separated by 69 nucleotidesRv3069 and Rv3070 overlap by 4 nucleotidesRv3070 and Rv3071 overlap by 4 nucleotidesRv3071 and Rv3072c are separated by 224 nucleotidesRv3072c and Rv3073c are separated by 6 nucleotides Rv3068c: Rv3068c - Probable phosphoglucomutase PgmA (glucose phosphomutase) (PGM), at 3,431,979 to 3,433,622 Rv3068c Rv3069: Rv3069 - Probable conserved transmembrane protein, at 3,433,692 to 3,434,090 Rv3069 Rv3070: Rv3070 - Probable conserved integral membrane protein, at 3,434,087 to 3,434,467 Rv3070 Rv3071: Rv3071 - Conserved hypothetical protein, at 3,434,464 to 3,435,573 Rv3071 Rv3072c: Rv3072c - Conserved hypothetical protein, at 3,435,798 to 3,436,322 Rv3072c Rv3073c: Rv3073c - Conserved hypothetical protein, at 3,436,329 to 3,436,685 Rv3073c Position (kb) 3434 3435 3436Strain fitness (log2 ratio) -1 0 1at 3433.546 kb on + strandat 3433.547 kb on - strandat 3433.668 kb on + strandat 3433.669 kb on - strandat 3433.669 kb on - strandat 3433.669 kb on - strandat 3433.852 kb on - strand, within Rv3069at 3433.894 kb on - strand, within Rv3069at 3434.081 kb on - strandat 3434.295 kb on + strand, within Rv3070at 3434.350 kb on - strand, within Rv3070at 3434.350 kb on - strand, within Rv3070at 3434.350 kb on - strand, within Rv3070at 3434.401 kb on + strand, within Rv3070at 3434.896 kb on + strand, within Rv3071at 3434.896 kb on + strand, within Rv3071at 3434.896 kb on + strand, within Rv3071at 3434.897 kb on - strand, within Rv3071at 3435.345 kb on + strand, within Rv3071at 3435.365 kb on + strand, within Rv3071at 3435.381 kb on + strand, within Rv3071at 3435.381 kb on + strand, within Rv3071at 3435.845 kb on - strandat 3435.949 kb on - strand, within Rv3072cat 3436.144 kb on + strand, within Rv3072cat 3436.145 kb on - strand, within Rv3072cat 3436.269 kb on + strand, within Rv3072cat 3436.270 kb on - strandat 3436.472 kb on - strand, within Rv3073c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM
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3,433,546 + -0.6
3,433,547 - -0.1
3,433,668 + -0.3
3,433,669 - +0.6
3,433,669 - -1.1
3,433,669 - -0.1
3,433,852 - Rv3069 0.40 +0.2
3,433,894 - Rv3069 0.51 +0.5
3,434,081 - -0.5
3,434,295 + Rv3070 0.55 +0.2
3,434,350 - Rv3070 0.69 -0.5
3,434,350 - Rv3070 0.69 -1.1
3,434,350 - Rv3070 0.69 +0.0
3,434,401 + Rv3070 0.82 -0.3
3,434,896 + Rv3071 0.39 +0.3
3,434,896 + Rv3071 0.39 -0.0
3,434,896 + Rv3071 0.39 -0.9
3,434,897 - Rv3071 0.39 +1.3
3,435,345 + Rv3071 0.79 -0.9
3,435,365 + Rv3071 0.81 -0.7
3,435,381 + Rv3071 0.83 +1.6
3,435,381 + Rv3071 0.83 +0.1
3,435,845 - -0.3
3,435,949 - Rv3072c 0.29 -0.3
3,436,144 + Rv3072c 0.66 -0.1
3,436,145 - Rv3072c 0.66 -0.4
3,436,269 + Rv3072c 0.90 -0.6
3,436,270 - -0.8
3,436,472 - Rv3073c 0.40 -0.4

Or see this region's nucleotide sequence