Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0206c

Experiment: 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv0205 and Rv0206c overlap by 4 nucleotidesRv0206c and Rv0207c are separated by 65 nucleotidesRv0207c and Rv0208c are separated by 2 nucleotides Rv0205: Rv0205 - Probable conserved transmembrane protein, at 243,384 to 244,487 Rv0205 Rv0206c: Rv0206c - Possible conserved transmembrane transport protein MmpL3, at 244,484 to 247,318 Rv0206c Rv0207c: Rv0207c - Conserved hypothetical protein, at 247,384 to 248,112 Rv0207c Rv0208c: Rv0208c - Hypothetical methlytransferase (methylase), at 248,115 to 248,906 Rv0208c Position (kb) 244 245 246 247 248Strain fitness (log2 ratio) -2 -1 0 1at 243.866 kb on + strand, within Rv0205at 243.867 kb on - strand, within Rv0205at 243.895 kb on + strand, within Rv0205at 243.895 kb on + strand, within Rv0205at 243.921 kb on + strand, within Rv0205at 243.945 kb on + strand, within Rv0205at 243.945 kb on + strand, within Rv0205at 243.946 kb on - strand, within Rv0205at 243.946 kb on - strand, within Rv0205at 244.485 kb on + strandat 244.486 kb on - strandat 244.623 kb on - strandat 244.623 kb on - strandat 247.723 kb on + strand, within Rv0207cat 247.724 kb on - strand, within Rv0207cat 247.724 kb on - strand, within Rv0207cat 248.053 kb on + strandat 248.120 kb on + strandat 248.206 kb on + strand, within Rv0208cat 248.206 kb on + strand, within Rv0208cat 248.311 kb on + strand, within Rv0208c

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM
remove
243,866 + Rv0205 0.44 -0.5
243,867 - Rv0205 0.44 +0.5
243,895 + Rv0205 0.46 +0.3
243,895 + Rv0205 0.46 +0.2
243,921 + Rv0205 0.49 -1.4
243,945 + Rv0205 0.51 +0.0
243,945 + Rv0205 0.51 -0.1
243,946 - Rv0205 0.51 -1.4
243,946 - Rv0205 0.51 -0.3
244,485 + +0.0
244,486 - -0.6
244,623 - -0.3
244,623 - -2.2
247,723 + Rv0207c 0.47 -0.6
247,724 - Rv0207c 0.47 -1.5
247,724 - Rv0207c 0.47 -0.4
248,053 + +0.2
248,120 + +0.3
248,206 + Rv0208c 0.11 +0.0
248,206 + Rv0208c 0.11 -0.6
248,311 + Rv0208c 0.25 -0.9

Or see this region's nucleotide sequence