Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2568c

Experiment: 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2567 and Rv2568c overlap by 4 nucleotidesRv2568c and Rv2569c overlap by 8 nucleotides Rv2567: Rv2567 - Conserved hypothetical alanine and leucine rich protein, at 2,889,795 to 2,892,449 Rv2567 Rv2568c: Rv2568c - Conserved hypothetical protein, at 2,892,446 to 2,893,471 Rv2568c Rv2569c: Rv2569c - Conserved hypothetical protein, at 2,893,464 to 2,894,408 Rv2569c Position (kb) 2892 2893 2894Strain fitness (log2 ratio) -2 -1 0 1 2at 2891.614 kb on - strand, within Rv2567at 2891.952 kb on - strand, within Rv2567at 2891.983 kb on + strand, within Rv2567at 2892.069 kb on - strand, within Rv2567at 2892.088 kb on + strand, within Rv2567at 2892.088 kb on + strand, within Rv2567at 2892.557 kb on + strand, within Rv2568cat 2892.558 kb on - strand, within Rv2568cat 2892.632 kb on - strand, within Rv2568cat 2892.897 kb on + strand, within Rv2568cat 2892.930 kb on + strand, within Rv2568cat 2892.930 kb on + strand, within Rv2568cat 2892.931 kb on - strand, within Rv2568cat 2892.931 kb on - strand, within Rv2568cat 2893.600 kb on + strand, within Rv2569cat 2893.601 kb on - strand, within Rv2569cat 2893.763 kb on - strand, within Rv2569cat 2893.763 kb on - strand, within Rv2569cat 2893.825 kb on - strand, within Rv2569cat 2893.904 kb on - strand, within Rv2569cat 2893.930 kb on - strand, within Rv2569cat 2893.930 kb on - strand, within Rv2569cat 2893.930 kb on - strand, within Rv2569cat 2893.930 kb on - strand, within Rv2569cat 2894.096 kb on - strand, within Rv2569cat 2894.096 kb on - strand, within Rv2569cat 2894.096 kb on - strand, within Rv2569cat 2894.180 kb on - strand, within Rv2569cat 2894.306 kb on - strand, within Rv2569cat 2894.415 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM
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2,891,614 - Rv2567 0.69 -1.6
2,891,952 - Rv2567 0.81 -1.9
2,891,983 + Rv2567 0.82 -2.7
2,892,069 - Rv2567 0.86 -0.2
2,892,088 + Rv2567 0.86 +0.2
2,892,088 + Rv2567 0.86 -1.6
2,892,557 + Rv2568c 0.11 -0.1
2,892,558 - Rv2568c 0.11 -0.6
2,892,632 - Rv2568c 0.18 +1.8
2,892,897 + Rv2568c 0.44 +0.8
2,892,930 + Rv2568c 0.47 -1.6
2,892,930 + Rv2568c 0.47 +0.3
2,892,931 - Rv2568c 0.47 -2.2
2,892,931 - Rv2568c 0.47 -0.8
2,893,600 + Rv2569c 0.14 +1.8
2,893,601 - Rv2569c 0.14 -1.0
2,893,763 - Rv2569c 0.32 -1.5
2,893,763 - Rv2569c 0.32 -0.8
2,893,825 - Rv2569c 0.38 -0.8
2,893,904 - Rv2569c 0.47 -0.6
2,893,930 - Rv2569c 0.49 -0.9
2,893,930 - Rv2569c 0.49 -1.7
2,893,930 - Rv2569c 0.49 -1.2
2,893,930 - Rv2569c 0.49 +1.8
2,894,096 - Rv2569c 0.67 +0.3
2,894,096 - Rv2569c 0.67 -1.5
2,894,096 - Rv2569c 0.67 -0.2
2,894,180 - Rv2569c 0.76 +1.2
2,894,306 - Rv2569c 0.89 -2.5
2,894,415 - -1.2

Or see this region's nucleotide sequence