Experiment: 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0305c and Rv0306 are separated by 202 nucleotides Rv0306 and Rv0307c overlap by 13 nucleotides Rv0307c and Rv0308 are separated by 57 nucleotides Rv0308 and Rv0309 are separated by 101 nucleotides
Rv0305c: Rv0305c - PPE family protein PPE6, at 372,820 to 375,711
Rv0305c
Rv0306: Rv0306 - Putative oxidoreductase, at 375,914 to 376,585
Rv0306
Rv0307c: Rv0307c - Unknown protein, at 376,573 to 377,055
Rv0307c
Rv0308: Rv0308 - Probable conserved integral membrane protein, at 377,113 to 377,829
Rv0308
Rv0309: Rv0309 - Possible conserved exported protein, at 377,931 to 378,587
Rv0309
Position (kb) 376
377
378 Strain fitness (log2 ratio) -2
-1
0
1
2 at 375.666 kb on - strand at 375.666 kb on - strand at 375.746 kb on + strand at 375.758 kb on - strand at 375.772 kb on + strand at 375.805 kb on + strand at 375.818 kb on + strand at 375.860 kb on - strand at 375.919 kb on + strand at 375.919 kb on + strand at 375.919 kb on + strand at 375.944 kb on + strand at 375.944 kb on + strand at 376.141 kb on - strand, within Rv0306 at 376.190 kb on + strand, within Rv0306 at 376.256 kb on + strand, within Rv0306 at 376.256 kb on + strand, within Rv0306 at 376.256 kb on + strand, within Rv0306 at 376.389 kb on + strand, within Rv0306 at 376.584 kb on - strand at 376.610 kb on + strand at 376.890 kb on - strand, within Rv0307c at 376.959 kb on - strand, within Rv0307c at 376.959 kb on - strand, within Rv0307c at 376.970 kb on + strand, within Rv0307c at 376.970 kb on + strand, within Rv0307c at 376.970 kb on + strand, within Rv0307c at 376.971 kb on - strand, within Rv0307c at 377.002 kb on + strand, within Rv0307c at 377.002 kb on + strand, within Rv0307c at 377.002 kb on + strand, within Rv0307c at 377.002 kb on + strand, within Rv0307c at 377.002 kb on + strand, within Rv0307c at 377.002 kb on + strand, within Rv0307c at 377.003 kb on - strand, within Rv0307c at 377.003 kb on - strand, within Rv0307c at 377.003 kb on - strand, within Rv0307c at 377.003 kb on - strand, within Rv0307c at 377.064 kb on + strand at 377.064 kb on + strand at 377.065 kb on - strand at 377.065 kb on - strand at 377.107 kb on + strand at 377.171 kb on - strand at 377.171 kb on - strand at 377.218 kb on - strand, within Rv0308 at 377.262 kb on - strand, within Rv0308 at 377.297 kb on + strand, within Rv0308 at 377.297 kb on + strand, within Rv0308 at 377.297 kb on + strand, within Rv0308 at 377.298 kb on - strand, within Rv0308 at 377.298 kb on - strand, within Rv0308 at 377.376 kb on - strand, within Rv0308 at 377.477 kb on + strand, within Rv0308 at 377.535 kb on - strand, within Rv0308 at 377.535 kb on - strand, within Rv0308 at 377.580 kb on + strand, within Rv0308 at 377.580 kb on + strand, within Rv0308 at 377.702 kb on - strand, within Rv0308 at 377.724 kb on - strand, within Rv0308 at 377.886 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM remove 375,666 - -0.7 375,666 - -1.5 375,746 + +0.3 375,758 - -0.3 375,772 + +0.0 375,805 + +0.5 375,818 + +0.1 375,860 - -1.6 375,919 + -0.3 375,919 + -0.9 375,919 + +0.2 375,944 + -1.3 375,944 + -0.3 376,141 - Rv0306 0.34 +0.2 376,190 + Rv0306 0.41 +1.1 376,256 + Rv0306 0.51 -0.5 376,256 + Rv0306 0.51 -1.7 376,256 + Rv0306 0.51 -1.8 376,389 + Rv0306 0.71 -0.1 376,584 - +1.0 376,610 + -1.7 376,890 - Rv0307c 0.66 -0.4 376,959 - Rv0307c 0.80 +0.2 376,959 - Rv0307c 0.80 +0.2 376,970 + Rv0307c 0.82 +0.4 376,970 + Rv0307c 0.82 +2.4 376,970 + Rv0307c 0.82 -0.1 376,971 - Rv0307c 0.82 +0.1 377,002 + Rv0307c 0.89 +1.0 377,002 + Rv0307c 0.89 -0.5 377,002 + Rv0307c 0.89 -0.5 377,002 + Rv0307c 0.89 -0.1 377,002 + Rv0307c 0.89 +1.3 377,002 + Rv0307c 0.89 +0.7 377,003 - Rv0307c 0.89 +0.4 377,003 - Rv0307c 0.89 +1.3 377,003 - Rv0307c 0.89 -0.7 377,003 - Rv0307c 0.89 +0.3 377,064 + +0.1 377,064 + -0.0 377,065 - -0.5 377,065 - -0.7 377,107 + -0.1 377,171 - -0.7 377,171 - -0.2 377,218 - Rv0308 0.15 +0.9 377,262 - Rv0308 0.21 -0.1 377,297 + Rv0308 0.26 -1.0 377,297 + Rv0308 0.26 +0.0 377,297 + Rv0308 0.26 -0.9 377,298 - Rv0308 0.26 -0.3 377,298 - Rv0308 0.26 -1.0 377,376 - Rv0308 0.37 -0.5 377,477 + Rv0308 0.51 -0.7 377,535 - Rv0308 0.59 -0.6 377,535 - Rv0308 0.59 +0.3 377,580 + Rv0308 0.65 -0.5 377,580 + Rv0308 0.65 +0.2 377,702 - Rv0308 0.82 -0.1 377,724 - Rv0308 0.85 +1.2 377,886 + +1.5
Or see this region's nucleotide sequence