Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2696c

Experiment: 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2695 and Rv2696c are separated by 205 nucleotidesRv2696c and Rv2697c are separated by 74 nucleotidesRv2697c and Rv2698 are separated by 25 nucleotides Rv2695: Rv2695 - Conserved hypothetical alanine rich protein, at 3,011,916 to 3,012,623 Rv2695 Rv2696c: Rv2696c - Conserved alanine and glycine and valine rich protein, at 3,012,829 to 3,013,608 Rv2696c Rv2697c: Rv2697c - Probable deoxyuridine 5'-triphosphate nucleotidohydrolase Dut (dUTPase) (dUTP pyrophosphatase) (deoxyuridine 5'-triphosphatase) (dUTP diphosphatase) (deoxyuridine-triphosphatase), at 3,013,683 to 3,014,147 Rv2697c Rv2698: Rv2698 - Probable conserved alanine rich transmembrane protein, at 3,014,173 to 3,014,658 Rv2698 Position (kb) 3012 3013 3014Strain fitness (log2 ratio) -2 -1 0 1 2at 3011.830 kb on + strandat 3011.831 kb on - strandat 3011.831 kb on - strandat 3011.847 kb on + strandat 3011.847 kb on + strandat 3011.907 kb on + strandat 3011.908 kb on - strandat 3011.908 kb on - strandat 3011.908 kb on - strandat 3011.908 kb on - strandat 3011.908 kb on - strandat 3011.979 kb on + strandat 3011.979 kb on + strandat 3011.979 kb on + strandat 3011.980 kb on - strandat 3012.226 kb on + strand, within Rv2695at 3012.227 kb on - strand, within Rv2695at 3012.227 kb on - strand, within Rv2695at 3012.314 kb on + strand, within Rv2695at 3012.314 kb on + strand, within Rv2695at 3012.315 kb on - strand, within Rv2695at 3012.383 kb on + strand, within Rv2695at 3012.383 kb on + strand, within Rv2695at 3012.383 kb on + strand, within Rv2695at 3012.402 kb on + strand, within Rv2695at 3012.403 kb on - strand, within Rv2695at 3012.515 kb on - strand, within Rv2695at 3012.654 kb on + strandat 3012.677 kb on + strandat 3012.716 kb on + strandat 3012.716 kb on + strandat 3012.717 kb on - strandat 3012.717 kb on - strandat 3012.742 kb on + strandat 3012.810 kb on + strandat 3012.811 kb on - strandat 3012.811 kb on - strandat 3012.811 kb on - strandat 3012.943 kb on + strand, within Rv2696cat 3012.944 kb on - strand, within Rv2696cat 3013.264 kb on - strand, within Rv2696cat 3013.355 kb on - strand, within Rv2696c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM
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3,011,830 + -2.3
3,011,831 - -0.2
3,011,831 - -1.3
3,011,847 + -1.0
3,011,847 + +0.4
3,011,907 + -0.3
3,011,908 - -1.0
3,011,908 - -0.1
3,011,908 - -0.5
3,011,908 - -0.6
3,011,908 - -0.5
3,011,979 + -1.5
3,011,979 + -1.3
3,011,979 + +2.1
3,011,980 - -0.9
3,012,226 + Rv2695 0.44 +0.0
3,012,227 - Rv2695 0.44 -0.1
3,012,227 - Rv2695 0.44 +0.2
3,012,314 + Rv2695 0.56 +0.2
3,012,314 + Rv2695 0.56 -0.2
3,012,315 - Rv2695 0.56 -0.8
3,012,383 + Rv2695 0.66 +0.6
3,012,383 + Rv2695 0.66 -0.2
3,012,383 + Rv2695 0.66 +0.5
3,012,402 + Rv2695 0.69 -0.7
3,012,403 - Rv2695 0.69 -0.2
3,012,515 - Rv2695 0.85 +0.1
3,012,654 + -0.7
3,012,677 + -0.6
3,012,716 + -0.6
3,012,716 + -0.5
3,012,717 - -0.6
3,012,717 - -0.4
3,012,742 + -0.1
3,012,810 + -1.6
3,012,811 - -0.1
3,012,811 - -0.3
3,012,811 - -0.3
3,012,943 + Rv2696c 0.15 -1.4
3,012,944 - Rv2696c 0.15 -0.3
3,013,264 - Rv2696c 0.56 -2.5
3,013,355 - Rv2696c 0.67 +0.7

Or see this region's nucleotide sequence