Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0862c

Experiment: 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0861c and Rv0862c are separated by 190 nucleotidesRv0862c and Rv0863 overlap by 14 nucleotidesRv0863 and Rv0864 are separated by 9 nucleotidesRv0864 and Rv0865 overlap by 4 nucleotides Rv0861c: Rv0861c - DNA helicase Ercc3, at 958,523 to 960,151 Rv0861c Rv0862c: Rv0862c - Conserved protein, at 960,342 to 962,612 Rv0862c Rv0863: Rv0863 - Conserved hypothetical protein, at 962,599 to 962,880 Rv0863 Rv0864: Rv0864 - Probable molybdenum cofactor biosynthesis protein C 2 MoaC2, at 962,890 to 963,393 Rv0864 Rv0865: Rv0865 - Probable molybdopterin biosynthesis Mog protein, at 963,390 to 963,872 Rv0865 Position (kb) 960 961 962 963Strain fitness (log2 ratio) -2 -1 0 1at 959.364 kb on + strand, within Rv0861cat 959.365 kb on - strand, within Rv0861cat 959.956 kb on - strand, within Rv0861cat 959.956 kb on - strand, within Rv0861cat 960.152 kb on + strandat 960.153 kb on - strandat 960.153 kb on - strandat 960.153 kb on - strandat 960.442 kb on - strandat 960.493 kb on + strandat 960.632 kb on + strand, within Rv0862cat 961.067 kb on - strand, within Rv0862cat 961.238 kb on + strand, within Rv0862cat 961.238 kb on + strand, within Rv0862cat 961.248 kb on + strand, within Rv0862cat 961.450 kb on - strand, within Rv0862cat 961.729 kb on - strand, within Rv0862cat 962.700 kb on + strand, within Rv0863at 962.700 kb on + strand, within Rv0863at 962.719 kb on + strand, within Rv0863at 962.719 kb on + strand, within Rv0863at 962.848 kb on + strand, within Rv0863at 962.849 kb on - strand, within Rv0863at 962.849 kb on - strand, within Rv0863at 963.023 kb on + strand, within Rv0864at 963.023 kb on + strand, within Rv0864at 963.023 kb on + strand, within Rv0864at 963.023 kb on + strand, within Rv0864at 963.024 kb on - strand, within Rv0864at 963.028 kb on - strand, within Rv0864at 963.111 kb on + strand, within Rv0864at 963.111 kb on + strand, within Rv0864at 963.166 kb on - strand, within Rv0864at 963.295 kb on + strand, within Rv0864at 963.295 kb on + strand, within Rv0864at 963.449 kb on + strand, within Rv0865at 963.554 kb on - strand, within Rv0865

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM
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959,364 + Rv0861c 0.52 -0.1
959,365 - Rv0861c 0.52 -0.2
959,956 - Rv0861c 0.88 +1.7
959,956 - Rv0861c 0.88 -1.3
960,152 + +0.2
960,153 - +0.7
960,153 - -1.2
960,153 - -1.0
960,442 - -1.5
960,493 + +0.3
960,632 + Rv0862c 0.13 +1.1
961,067 - Rv0862c 0.32 -0.8
961,238 + Rv0862c 0.39 +0.2
961,238 + Rv0862c 0.39 +0.8
961,248 + Rv0862c 0.40 +1.6
961,450 - Rv0862c 0.49 +0.4
961,729 - Rv0862c 0.61 +0.7
962,700 + Rv0863 0.36 -0.0
962,700 + Rv0863 0.36 -0.3
962,719 + Rv0863 0.43 -0.7
962,719 + Rv0863 0.43 +0.9
962,848 + Rv0863 0.88 -0.6
962,849 - Rv0863 0.89 +0.1
962,849 - Rv0863 0.89 +0.1
963,023 + Rv0864 0.26 +0.3
963,023 + Rv0864 0.26 -0.2
963,023 + Rv0864 0.26 -0.5
963,023 + Rv0864 0.26 -0.3
963,024 - Rv0864 0.27 -0.3
963,028 - Rv0864 0.27 -0.4
963,111 + Rv0864 0.44 -1.1
963,111 + Rv0864 0.44 -1.4
963,166 - Rv0864 0.55 -1.3
963,295 + Rv0864 0.80 +0.1
963,295 + Rv0864 0.80 -0.5
963,449 + Rv0865 0.12 -2.0
963,554 - Rv0865 0.34 +0.9

Or see this region's nucleotide sequence