Experiment: 7H9 with Lomefloxacin 0.0035 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv2761c and Rv2762c overlap by 4 nucleotides Rv2762c and Rv2763c are separated by 73 nucleotides Rv2763c and Rv2764c are separated by 70 nucleotides
Rv2761c: Rv2761c - Possible type I restriction/modification system specificity determinant HsdS (S protein), at 3,071,546 to 3,072,640
Rv2761c
Rv2762c: Rv2762c - Conserved hypothetical protein, at 3,072,637 to 3,073,056
Rv2762c
Rv2763c: Rv2763c - Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase), at 3,073,130 to 3,073,609
Rv2763c
Rv2764c: Rv2764c - Probable thymidylate synthase ThyA (ts) (TSASE), at 3,073,680 to 3,074,471
Rv2764c
Position (kb)
3072
3073
3074 Strain fitness (log2 ratio)
-1
0
1
2 at 3072.039 kb on + strand, within Rv2761c at 3072.040 kb on - strand, within Rv2761c at 3072.117 kb on + strand, within Rv2761c at 3072.118 kb on - strand, within Rv2761c at 3072.118 kb on - strand, within Rv2761c at 3072.118 kb on - strand, within Rv2761c at 3072.345 kb on + strand, within Rv2761c at 3072.346 kb on - strand, within Rv2761c at 3072.441 kb on + strand, within Rv2761c at 3072.523 kb on - strand, within Rv2761c at 3072.574 kb on + strand at 3072.605 kb on + strand at 3072.611 kb on + strand at 3072.778 kb on + strand, within Rv2762c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Lomefloxacin 0.0035 mM remove 3,072,039 + Rv2761c 0.45 -0.4 3,072,040 - Rv2761c 0.45 -0.5 3,072,117 + Rv2761c 0.52 +0.8 3,072,118 - Rv2761c 0.52 -0.2 3,072,118 - Rv2761c 0.52 -1.5 3,072,118 - Rv2761c 0.52 +1.8 3,072,345 + Rv2761c 0.73 -0.2 3,072,346 - Rv2761c 0.73 +0.2 3,072,441 + Rv2761c 0.82 -0.8 3,072,523 - Rv2761c 0.89 -0.3 3,072,574 + -0.2 3,072,605 + -0.6 3,072,611 + +0.0 3,072,778 + Rv2762c 0.34 +1.1
Or see this region's nucleotide sequence