Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2214c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2213 and Rv2214c are separated by 37 nucleotidesRv2214c and Rv2215 are separated by 263 nucleotides Rv2213: Rv2213 - Probable aminopeptidase PepB, at 2,478,338 to 2,479,885 Rv2213 Rv2214c: Rv2214c - Possible short-chain dehydrogenase EphD, at 2,479,923 to 2,481,701 Rv2214c Rv2215: Rv2215 - DlaT, dihydrolipoamide acyltransferase, E2 component of pyruvate dehydrogenase, at 2,481,965 to 2,483,626 Rv2215 Position (kb) 2479 2480 2481 2482Strain fitness (log2 ratio) -1 0 1 2at 2479.481 kb on + strand, within Rv2213at 2479.482 kb on - strand, within Rv2213at 2479.784 kb on + strandat 2479.784 kb on + strandat 2479.784 kb on + strandat 2479.785 kb on - strandat 2479.925 kb on - strandat 2479.947 kb on - strandat 2479.984 kb on + strandat 2479.985 kb on - strandat 2479.986 kb on + strandat 2479.993 kb on + strandat 2479.993 kb on + strandat 2480.074 kb on + strandat 2480.074 kb on + strandat 2480.257 kb on + strand, within Rv2214cat 2480.257 kb on + strand, within Rv2214cat 2480.258 kb on - strand, within Rv2214cat 2480.258 kb on - strand, within Rv2214cat 2480.258 kb on - strand, within Rv2214cat 2480.258 kb on - strand, within Rv2214cat 2480.308 kb on + strand, within Rv2214cat 2480.569 kb on + strand, within Rv2214cat 2480.569 kb on + strand, within Rv2214cat 2480.569 kb on + strand, within Rv2214cat 2480.569 kb on + strand, within Rv2214cat 2480.926 kb on + strand, within Rv2214cat 2480.927 kb on - strand, within Rv2214cat 2480.939 kb on - strand, within Rv2214cat 2480.939 kb on - strand, within Rv2214cat 2480.982 kb on + strand, within Rv2214cat 2480.983 kb on - strand, within Rv2214cat 2481.040 kb on + strand, within Rv2214cat 2481.199 kb on + strand, within Rv2214cat 2481.200 kb on - strand, within Rv2214cat 2481.272 kb on - strand, within Rv2214cat 2481.277 kb on + strand, within Rv2214cat 2481.277 kb on + strand, within Rv2214cat 2481.359 kb on - strand, within Rv2214cat 2481.521 kb on - strand, within Rv2214cat 2481.637 kb on + strandat 2481.752 kb on - strandat 2481.863 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,479,481 + Rv2213 0.74 -0.1
2,479,482 - Rv2213 0.74 -0.4
2,479,784 + -0.4
2,479,784 + +1.9
2,479,784 + +0.2
2,479,785 - -1.1
2,479,925 - +0.9
2,479,947 - -0.4
2,479,984 + -0.1
2,479,985 - -0.5
2,479,986 + +0.2
2,479,993 + -0.0
2,479,993 + -0.2
2,480,074 + +0.3
2,480,074 + +0.3
2,480,257 + Rv2214c 0.19 +0.6
2,480,257 + Rv2214c 0.19 -1.1
2,480,258 - Rv2214c 0.19 -0.2
2,480,258 - Rv2214c 0.19 +0.5
2,480,258 - Rv2214c 0.19 -0.1
2,480,258 - Rv2214c 0.19 +0.6
2,480,308 + Rv2214c 0.22 +1.2
2,480,569 + Rv2214c 0.36 +1.5
2,480,569 + Rv2214c 0.36 +0.0
2,480,569 + Rv2214c 0.36 -0.2
2,480,569 + Rv2214c 0.36 +0.2
2,480,926 + Rv2214c 0.56 +1.0
2,480,927 - Rv2214c 0.56 +1.8
2,480,939 - Rv2214c 0.57 -0.1
2,480,939 - Rv2214c 0.57 -0.7
2,480,982 + Rv2214c 0.60 -0.8
2,480,983 - Rv2214c 0.60 +1.9
2,481,040 + Rv2214c 0.63 +0.9
2,481,199 + Rv2214c 0.72 +0.9
2,481,200 - Rv2214c 0.72 +0.9
2,481,272 - Rv2214c 0.76 +0.2
2,481,277 + Rv2214c 0.76 -0.5
2,481,277 + Rv2214c 0.76 +0.7
2,481,359 - Rv2214c 0.81 +0.1
2,481,521 - Rv2214c 0.90 +0.7
2,481,637 + +0.1
2,481,752 - -0.1
2,481,863 + -0.4

Or see this region's nucleotide sequence