Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1112

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1111c and Rv1112 are separated by 62 nucleotidesRv1112 and Rv1113 are separated by 87 nucleotidesRv1113 and Rv1114 overlap by 4 nucleotidesRv1114 and Rv1115 are separated by 202 nucleotides Rv1111c: Rv1111c - Conserved hypothetical protein, at 1,237,209 to 1,238,192 Rv1111c Rv1112: Rv1112 - Probable GTP binding protein, at 1,238,255 to 1,239,328 Rv1112 Rv1113: Rv1113 - Possible antitoxin VapB32, at 1,239,416 to 1,239,613 Rv1113 Rv1114: Rv1114 - Possible toxin VapC32. Contains PIN domain., at 1,239,610 to 1,239,984 Rv1114 Rv1115: Rv1115 - Possible exported protein, at 1,240,187 to 1,240,885 Rv1115 Position (kb) 1238 1239 1240Strain fitness (log2 ratio) -2 -1 0 1at 1237.294 kb on + strandat 1237.295 kb on - strandat 1237.295 kb on - strandat 1237.295 kb on - strandat 1237.408 kb on + strand, within Rv1111cat 1237.421 kb on - strand, within Rv1111cat 1237.459 kb on + strand, within Rv1111cat 1237.775 kb on - strand, within Rv1111cat 1237.775 kb on - strand, within Rv1111cat 1238.349 kb on - strandat 1238.853 kb on - strand, within Rv1112at 1238.853 kb on - strand, within Rv1112at 1238.853 kb on - strand, within Rv1112at 1239.282 kb on - strandat 1239.303 kb on + strandat 1239.327 kb on - strandat 1239.327 kb on - strandat 1239.451 kb on - strand, within Rv1113at 1239.782 kb on - strand, within Rv1114at 1239.911 kb on + strand, within Rv1114at 1239.989 kb on + strandat 1239.989 kb on + strandat 1239.989 kb on + strandat 1239.990 kb on - strandat 1240.298 kb on + strand, within Rv1115

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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1,237,294 + -0.7
1,237,295 - -1.9
1,237,295 - -0.1
1,237,295 - +0.6
1,237,408 + Rv1111c 0.20 +1.7
1,237,421 - Rv1111c 0.22 -0.2
1,237,459 + Rv1111c 0.25 -0.5
1,237,775 - Rv1111c 0.58 +0.2
1,237,775 - Rv1111c 0.58 -0.8
1,238,349 - -0.7
1,238,853 - Rv1112 0.56 +0.9
1,238,853 - Rv1112 0.56 +0.9
1,238,853 - Rv1112 0.56 +1.5
1,239,282 - +0.0
1,239,303 + +0.8
1,239,327 - +0.0
1,239,327 - -0.4
1,239,451 - Rv1113 0.18 -0.6
1,239,782 - Rv1114 0.46 -0.5
1,239,911 + Rv1114 0.80 +0.1
1,239,989 + -0.3
1,239,989 + -1.4
1,239,989 + -0.1
1,239,990 - +0.9
1,240,298 + Rv1115 0.16 +0.7

Or see this region's nucleotide sequence