Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0771

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0769 and Rv0770 are separated by 97 nucleotidesRv0770 and Rv0771 overlap by 4 nucleotidesRv0771 and Rv0772 are separated by 11 nucleotides Rv0769: Rv0769 - Probable dehydrogenase/reductase, at 862,412 to 863,158 Rv0769 Rv0770: Rv0770 - Probable dehydrogenase/reductase, at 863,256 to 864,143 Rv0770 Rv0771: Rv0771 - Possible 4-carboxymuconolactone decarboxylase (CMD), at 864,140 to 864,574 Rv0771 Rv0772: Rv0772 - Probable phosphoribosylamine--glycine ligase PurD (GARS) (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase) (5'-phosphoribosylglycinamide synthetase), at 864,586 to 865,854 Rv0772 Position (kb) 864 865Strain fitness (log2 ratio) -1 0 1at 863.289 kb on + strandat 863.291 kb on + strandat 863.291 kb on + strandat 864.246 kb on + strand, within Rv0771at 864.247 kb on - strand, within Rv0771at 864.370 kb on + strand, within Rv0771at 864.387 kb on + strand, within Rv0771at 864.388 kb on - strand, within Rv0771at 864.388 kb on - strand, within Rv0771at 864.573 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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863,289 + -0.4
863,291 + -0.9
863,291 + -0.6
864,246 + Rv0771 0.24 +0.8
864,247 - Rv0771 0.25 -0.5
864,370 + Rv0771 0.53 +0.5
864,387 + Rv0771 0.57 -0.3
864,388 - Rv0771 0.57 +0.2
864,388 - Rv0771 0.57 +0.9
864,573 - -0.1

Or see this region's nucleotide sequence