Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1158c

Experiment: 7H9 with Benzethonium chloride 0.068 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1157c and Rv1158c are separated by 7 nucleotidesRv1158c and Rv1159 are separated by 129 nucleotides Rv1157c: Rv1157c - Conserved ala-, pro-rich protein, at 1,283,056 to 1,284,171 Rv1157c Rv1158c: Rv1158c - Conserved hypothetical ala-, pro-rich protein, at 1,284,179 to 1,284,862 Rv1158c Rv1159: Rv1159 - Mannosyltransferase PimE, at 1,284,992 to 1,286,287 Rv1159 Position (kb) 1284 1285Strain fitness (log2 ratio) -3 -2 -1 0 1 2 3at 1284.426 kb on - strand, within Rv1158cat 1284.510 kb on - strand, within Rv1158cat 1284.551 kb on + strand, within Rv1158cat 1284.800 kb on + strandat 1284.801 kb on - strandat 1284.801 kb on - strandat 1284.943 kb on - strandat 1284.943 kb on - strandat 1284.953 kb on + strandat 1285.050 kb on + strandat 1285.050 kb on + strandat 1285.050 kb on + strandat 1285.253 kb on + strand, within Rv1159at 1285.381 kb on - strand, within Rv1159at 1285.754 kb on + strand, within Rv1159

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Benzethonium chloride 0.068 mM
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1,284,426 - Rv1158c 0.36 +1.0
1,284,510 - Rv1158c 0.48 +0.9
1,284,551 + Rv1158c 0.54 +2.8
1,284,800 + -0.6
1,284,801 - -0.4
1,284,801 - -0.0
1,284,943 - -1.3
1,284,943 - -0.4
1,284,953 + -0.4
1,285,050 + +0.1
1,285,050 + -0.1
1,285,050 + +0.2
1,285,253 + Rv1159 0.20 -1.7
1,285,381 - Rv1159 0.30 -1.7
1,285,754 + Rv1159 0.59 -3.6

Or see this region's nucleotide sequence