Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3657c

Experiment: 7H9 with Benzethonium chloride 0.068 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3654c and Rv3655c are separated by 8 nucleotidesRv3655c and Rv3656c are separated by 23 nucleotidesRv3656c and Rv3657c are separated by 9 nucleotidesRv3657c and Rv3658c are separated by 23 nucleotidesRv3658c and Rv3659c overlap by 4 nucleotides Rv3654c: Rv3654c - Conserved hypothetical protein, at 4,094,660 to 4,094,914 Rv3654c Rv3655c: Rv3655c - Conserved hypothetical protein, at 4,094,923 to 4,095,300 Rv3655c Rv3656c: Rv3656c - Conserved hypothetical protein, at 4,095,324 to 4,095,530 Rv3656c Rv3657c: Rv3657c - Possible conserved alanine rich membrane protein, at 4,095,540 to 4,096,115 Rv3657c Rv3658c: Rv3658c - Probable conserved transmembrane protein, at 4,096,139 to 4,096,939 Rv3658c Rv3659c: Rv3659c - Conserved hypothetical protein, at 4,096,936 to 4,097,994 Rv3659c Position (kb) 4095 4096 4097Strain fitness (log2 ratio) -2 -1 0 1 2at 4094.562 kb on - strandat 4094.585 kb on - strandat 4094.613 kb on - strandat 4094.613 kb on - strandat 4094.650 kb on + strandat 4094.924 kb on + strandat 4094.924 kb on + strandat 4094.929 kb on - strandat 4095.164 kb on - strand, within Rv3655cat 4095.164 kb on - strand, within Rv3655cat 4095.210 kb on + strand, within Rv3655cat 4095.211 kb on - strand, within Rv3655cat 4095.445 kb on + strand, within Rv3656cat 4095.531 kb on - strandat 4095.583 kb on - strandat 4095.777 kb on + strand, within Rv3657cat 4096.023 kb on + strand, within Rv3657cat 4096.310 kb on + strand, within Rv3658cat 4096.711 kb on - strand, within Rv3658cat 4096.930 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Benzethonium chloride 0.068 mM
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4,094,562 - -0.0
4,094,585 - +0.1
4,094,613 - +0.4
4,094,613 - -0.0
4,094,650 + +2.7
4,094,924 + +0.0
4,094,924 + -0.3
4,094,929 - -0.2
4,095,164 - Rv3655c 0.64 -1.0
4,095,164 - Rv3655c 0.64 -1.8
4,095,210 + Rv3655c 0.76 +1.3
4,095,211 - Rv3655c 0.76 +0.4
4,095,445 + Rv3656c 0.58 +0.9
4,095,531 - -0.3
4,095,583 - -0.2
4,095,777 + Rv3657c 0.41 -0.7
4,096,023 + Rv3657c 0.84 -0.9
4,096,310 + Rv3658c 0.21 +0.0
4,096,711 - Rv3658c 0.71 +0.0
4,096,930 + +0.0

Or see this region's nucleotide sequence