Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2968c

Experiment: 7H9 with Benzethonium chloride 0.068 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2967c and Rv2968c are separated by 24 nucleotidesRv2968c and Rv2969c are separated by 5 nucleotidesRv2969c and Rv2970c are separated by 96 nucleotides Rv2967c: Rv2967c - Probable pyruvate carboxylase Pca (pyruvic carboxylase), at 3,319,663 to 3,323,046 Rv2967c Rv2968c: Rv2968c - Probable conserved integral membrane protein, at 3,323,071 to 3,323,703 Rv2968c Rv2969c: Rv2969c - Possible conserved membrane or secreted protein, at 3,323,709 to 3,324,476 Rv2969c Rv2970c: Rv2970c - Probable lipase/esterase LipN, at 3,324,573 to 3,325,703 Rv2970c Position (kb) 3323 3324Strain fitness (log2 ratio) -2 -1 0 1at 3322.196 kb on + strand, within Rv2967cat 3322.197 kb on - strand, within Rv2967cat 3322.374 kb on - strand, within Rv2967cat 3322.374 kb on - strand, within Rv2967cat 3322.808 kb on + strandat 3322.812 kb on + strandat 3322.865 kb on + strandat 3322.865 kb on + strandat 3322.865 kb on + strandat 3322.866 kb on - strandat 3322.866 kb on - strandat 3322.946 kb on + strandat 3322.953 kb on - strandat 3324.545 kb on - strandat 3324.550 kb on - strandat 3324.585 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Benzethonium chloride 0.068 mM
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3,322,196 + Rv2967c 0.75 -1.3
3,322,197 - Rv2967c 0.75 -1.9
3,322,374 - Rv2967c 0.80 -0.6
3,322,374 - Rv2967c 0.80 -1.1
3,322,808 + -2.0
3,322,812 + -0.6
3,322,865 + -0.2
3,322,865 + +0.1
3,322,865 + -1.3
3,322,866 - -0.9
3,322,866 - -0.5
3,322,946 + -1.0
3,322,953 - -0.4
3,324,545 - +0.2
3,324,550 - -0.6
3,324,585 - -0.1

Or see this region's nucleotide sequence