Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2766c

Experiment: 7H9 with Chlorpromazine 0.054 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2765 and Rv2766c are separated by 214 nucleotidesRv2766c and Rv2767c overlap by 4 nucleotidesRv2767c and Rv2768c are separated by 173 nucleotides Rv2765: Rv2765 - Probable alanine rich hydrolase, at 3,074,636 to 3,075,373 Rv2765 Rv2766c: Rv2766c - Probable short-chain type dehydrogenase/reductase, at 3,075,588 to 3,076,370 Rv2766c Rv2767c: Rv2767c - Possible membrane protein, at 3,076,367 to 3,076,720 Rv2767c Rv2768c: Rv2768c - PPE family protein PPE43, at 3,076,894 to 3,078,078 Rv2768c Position (kb) 3075 3076 3077Strain fitness (log2 ratio) -2 -1 0 1at 3074.598 kb on + strandat 3074.599 kb on - strandat 3074.624 kb on - strandat 3074.802 kb on - strand, within Rv2765at 3074.802 kb on - strand, within Rv2765at 3074.825 kb on + strand, within Rv2765at 3074.825 kb on + strand, within Rv2765at 3074.825 kb on + strand, within Rv2765at 3074.826 kb on - strand, within Rv2765at 3074.826 kb on - strand, within Rv2765at 3074.829 kb on - strand, within Rv2765at 3074.905 kb on + strand, within Rv2765at 3074.906 kb on - strand, within Rv2765at 3074.963 kb on + strand, within Rv2765at 3074.963 kb on + strand, within Rv2765at 3074.964 kb on - strand, within Rv2765at 3074.964 kb on - strand, within Rv2765at 3074.964 kb on - strand, within Rv2765at 3075.015 kb on - strand, within Rv2765at 3075.263 kb on + strand, within Rv2765at 3075.513 kb on + strandat 3075.513 kb on + strandat 3075.513 kb on + strandat 3075.717 kb on + strand, within Rv2766cat 3075.907 kb on + strand, within Rv2766cat 3075.907 kb on + strand, within Rv2766cat 3075.907 kb on + strand, within Rv2766cat 3075.908 kb on - strand, within Rv2766cat 3075.908 kb on - strand, within Rv2766cat 3075.908 kb on - strand, within Rv2766cat 3075.908 kb on - strand, within Rv2766cat 3076.331 kb on + strandat 3076.335 kb on + strandat 3076.335 kb on + strandat 3076.336 kb on - strandat 3076.336 kb on - strandat 3076.458 kb on - strand, within Rv2767cat 3076.458 kb on - strand, within Rv2767cat 3076.581 kb on - strand, within Rv2767cat 3076.581 kb on - strand, within Rv2767cat 3076.581 kb on - strand, within Rv2767cat 3076.605 kb on - strand, within Rv2767cat 3076.710 kb on + strandat 3076.711 kb on - strandat 3076.937 kb on + strandat 3076.952 kb on + strandat 3076.953 kb on - strandat 3077.061 kb on + strand, within Rv2768cat 3077.361 kb on + strand, within Rv2768c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Chlorpromazine 0.054 mM
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3,074,598 + -0.5
3,074,599 - +0.8
3,074,624 - +0.1
3,074,802 - Rv2765 0.22 -0.0
3,074,802 - Rv2765 0.22 -2.7
3,074,825 + Rv2765 0.26 -0.1
3,074,825 + Rv2765 0.26 -0.4
3,074,825 + Rv2765 0.26 -0.6
3,074,826 - Rv2765 0.26 -1.0
3,074,826 - Rv2765 0.26 +0.0
3,074,829 - Rv2765 0.26 -1.0
3,074,905 + Rv2765 0.36 +0.7
3,074,906 - Rv2765 0.37 -0.1
3,074,963 + Rv2765 0.44 +0.7
3,074,963 + Rv2765 0.44 -0.4
3,074,964 - Rv2765 0.44 -0.6
3,074,964 - Rv2765 0.44 -0.2
3,074,964 - Rv2765 0.44 -0.6
3,075,015 - Rv2765 0.51 -0.1
3,075,263 + Rv2765 0.85 -0.7
3,075,513 + -0.2
3,075,513 + -0.7
3,075,513 + -1.8
3,075,717 + Rv2766c 0.16 -0.2
3,075,907 + Rv2766c 0.41 +1.4
3,075,907 + Rv2766c 0.41 -0.4
3,075,907 + Rv2766c 0.41 +0.2
3,075,908 - Rv2766c 0.41 +0.5
3,075,908 - Rv2766c 0.41 +0.9
3,075,908 - Rv2766c 0.41 +0.7
3,075,908 - Rv2766c 0.41 +0.7
3,076,331 + +0.1
3,076,335 + -1.3
3,076,335 + -0.7
3,076,336 - -0.6
3,076,336 - -0.5
3,076,458 - Rv2767c 0.26 -0.7
3,076,458 - Rv2767c 0.26 +0.1
3,076,581 - Rv2767c 0.60 -0.3
3,076,581 - Rv2767c 0.60 +1.1
3,076,581 - Rv2767c 0.60 +0.4
3,076,605 - Rv2767c 0.67 +0.3
3,076,710 + -0.9
3,076,711 - +0.2
3,076,937 + +1.7
3,076,952 + +0.2
3,076,953 - -0.5
3,077,061 + Rv2768c 0.14 -0.1
3,077,361 + Rv2768c 0.39 -0.0

Or see this region's nucleotide sequence