Experiment: 7H9 with Chlorpromazine 0.054 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0647c and Rv0648 are separated by 101 nucleotides Rv0648 and Rv0649 overlap by 4 nucleotides Rv0649 and Rv0650 overlap by 1 nucleotides
Rv0647c: Rv0647c - Conserved protein, at 741,151 to 742,617
Rv0647c
Rv0648: Rv0648 - Alpha-mannosidase, at 742,719 to 746,366
Rv0648
Rv0649: Rv0649 - Possible malonyl CoA-acyl carrier protein transacylase FabD2 (MCT), at 746,363 to 747,037
Rv0649
Rv0650: Rv0650 - Possible sugar kinase, at 747,037 to 747,945
Rv0650
Position (kb) 742
743
744
745
746
747 Strain fitness (log2 ratio) -2
-1
0
1 at 742.580 kb on + strand at 742.581 kb on - strand at 742.618 kb on + strand at 742.618 kb on + strand at 742.641 kb on + strand at 742.661 kb on + strand at 742.963 kb on + strand at 742.963 kb on + strand at 742.964 kb on - strand at 743.031 kb on + strand at 743.031 kb on + strand at 743.032 kb on - strand at 743.032 kb on - strand at 743.032 kb on - strand at 743.032 kb on - strand at 743.106 kb on + strand, within Rv0648 at 743.175 kb on + strand, within Rv0648 at 743.176 kb on - strand, within Rv0648 at 743.176 kb on - strand, within Rv0648 at 743.347 kb on - strand, within Rv0648 at 743.347 kb on - strand, within Rv0648 at 743.367 kb on + strand, within Rv0648 at 743.367 kb on + strand, within Rv0648 at 743.367 kb on + strand, within Rv0648 at 743.464 kb on - strand, within Rv0648 at 743.505 kb on + strand, within Rv0648 at 743.506 kb on - strand, within Rv0648 at 743.506 kb on - strand, within Rv0648 at 743.506 kb on - strand, within Rv0648 at 743.554 kb on - strand, within Rv0648 at 744.024 kb on + strand, within Rv0648 at 744.024 kb on + strand, within Rv0648 at 744.033 kb on + strand, within Rv0648 at 744.034 kb on - strand, within Rv0648 at 744.073 kb on + strand, within Rv0648 at 744.073 kb on + strand, within Rv0648 at 744.074 kb on - strand, within Rv0648 at 744.074 kb on - strand, within Rv0648 at 744.075 kb on - strand, within Rv0648 at 744.189 kb on + strand, within Rv0648 at 744.426 kb on + strand, within Rv0648 at 744.426 kb on + strand, within Rv0648 at 744.427 kb on - strand, within Rv0648 at 744.717 kb on + strand, within Rv0648 at 745.156 kb on - strand, within Rv0648 at 745.456 kb on + strand, within Rv0648 at 745.456 kb on + strand, within Rv0648 at 745.456 kb on + strand, within Rv0648 at 745.457 kb on - strand, within Rv0648 at 745.590 kb on - strand, within Rv0648 at 745.651 kb on - strand, within Rv0648 at 746.058 kb on + strand at 746.058 kb on + strand at 746.058 kb on + strand at 746.059 kb on - strand at 746.225 kb on - strand at 746.334 kb on + strand at 746.789 kb on + strand, within Rv0649 at 746.789 kb on + strand, within Rv0649 at 746.790 kb on - strand, within Rv0649 at 746.790 kb on - strand, within Rv0649 at 746.790 kb on - strand, within Rv0649 at 746.988 kb on - strand at 747.246 kb on + strand, within Rv0650 at 747.254 kb on + strand, within Rv0650
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Chlorpromazine 0.054 mM remove 742,580 + +0.2 742,581 - +0.6 742,618 + -0.9 742,618 + -0.5 742,641 + -0.1 742,661 + -0.3 742,963 + +0.0 742,963 + -0.5 742,964 - +0.1 743,031 + -0.6 743,031 + -0.3 743,032 - +1.3 743,032 - +0.1 743,032 - -0.0 743,032 - -0.6 743,106 + Rv0648 0.11 -1.9 743,175 + Rv0648 0.12 +0.0 743,176 - Rv0648 0.13 -0.6 743,176 - Rv0648 0.13 +0.4 743,347 - Rv0648 0.17 -0.4 743,347 - Rv0648 0.17 +0.2 743,367 + Rv0648 0.18 +0.2 743,367 + Rv0648 0.18 -0.9 743,367 + Rv0648 0.18 -0.2 743,464 - Rv0648 0.20 +0.6 743,505 + Rv0648 0.22 -0.8 743,506 - Rv0648 0.22 -0.3 743,506 - Rv0648 0.22 +0.3 743,506 - Rv0648 0.22 -0.6 743,554 - Rv0648 0.23 -0.4 744,024 + Rv0648 0.36 -0.2 744,024 + Rv0648 0.36 -0.9 744,033 + Rv0648 0.36 +0.8 744,034 - Rv0648 0.36 -0.6 744,073 + Rv0648 0.37 -0.6 744,073 + Rv0648 0.37 -0.5 744,074 - Rv0648 0.37 -0.0 744,074 - Rv0648 0.37 -0.6 744,075 - Rv0648 0.37 -0.3 744,189 + Rv0648 0.40 -0.3 744,426 + Rv0648 0.47 -0.1 744,426 + Rv0648 0.47 +0.5 744,427 - Rv0648 0.47 +0.1 744,717 + Rv0648 0.55 +1.7 745,156 - Rv0648 0.67 -0.1 745,456 + Rv0648 0.75 -0.2 745,456 + Rv0648 0.75 -1.0 745,456 + Rv0648 0.75 -0.6 745,457 - Rv0648 0.75 -0.2 745,590 - Rv0648 0.79 -0.4 745,651 - Rv0648 0.80 +0.5 746,058 + -0.3 746,058 + -0.5 746,058 + +0.1 746,059 - -0.3 746,225 - +1.1 746,334 + -0.1 746,789 + Rv0649 0.63 +1.7 746,789 + Rv0649 0.63 +0.8 746,790 - Rv0649 0.63 +0.6 746,790 - Rv0649 0.63 +0.1 746,790 - Rv0649 0.63 -1.3 746,988 - -0.6 747,246 + Rv0650 0.23 -0.3 747,254 + Rv0650 0.24 -0.0
Or see this region's nucleotide sequence