Experiment: 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0755c and Rv0755A are separated by 301 nucleotides Rv0755A and GFF789 are separated by 114 nucleotides GFF789 and Rv0756c are separated by 27 nucleotides Rv0756c and Rv0757 are separated by 141 nucleotides Rv0757 and Rv0758 are separated by 44 nucleotides
Rv0755c: Rv0755c - PPE family protein PPE12, at 848,103 to 850,040
Rv0755c
Rv0755A: Rv0755A - Putative transposase (fragment), at 850,342 to 850,527
Rv0755A
GFF789 - tRNA-Thr, at 850,642 to 850,713
GFF789
Rv0756c: Rv0756c - Unknown protein, at 850,741 to 851,466
Rv0756c
Rv0757: Rv0757 - Possible two component system response transcriptional positive regulator PhoP, at 851,608 to 852,351
Rv0757
Rv0758: Rv0758 - Possible two component system response sensor kinase membrane associated PhoR, at 852,396 to 853,853
Rv0758
Position (kb)
850
851
852 Strain fitness (log2 ratio)
-2
-1
0
1
2
3
4
5 at 849.824 kb on - strand, within Rv0755c at 849.966 kb on + strand at 849.991 kb on + strand at 849.991 kb on + strand at 849.992 kb on - strand at 850.084 kb on + strand at 850.085 kb on - strand at 850.088 kb on + strand at 850.088 kb on + strand at 850.088 kb on + strand at 850.089 kb on - strand at 850.089 kb on - strand at 850.089 kb on - strand at 850.115 kb on + strand at 850.343 kb on + strand at 850.344 kb on - strand at 850.344 kb on - strand at 850.344 kb on - strand at 850.345 kb on + strand at 850.345 kb on + strand at 850.345 kb on + strand at 850.345 kb on + strand at 850.346 kb on - strand at 850.346 kb on - strand at 850.346 kb on - strand at 850.346 kb on - strand at 850.346 kb on - strand at 850.346 kb on - strand at 850.346 kb on - strand at 850.346 kb on - strand at 850.346 kb on - strand at 850.369 kb on + strand, within Rv0755A at 850.369 kb on + strand, within Rv0755A at 850.369 kb on + strand, within Rv0755A at 850.395 kb on - strand, within Rv0755A at 850.410 kb on + strand, within Rv0755A at 850.410 kb on + strand, within Rv0755A at 850.410 kb on + strand, within Rv0755A at 850.411 kb on - strand, within Rv0755A at 850.497 kb on - strand, within Rv0755A at 850.625 kb on + strand at 850.628 kb on + strand at 850.628 kb on + strand at 850.628 kb on + strand at 850.629 kb on - strand at 850.629 kb on - strand at 850.629 kb on - strand at 850.860 kb on + strand, within Rv0756c at 850.860 kb on + strand, within Rv0756c at 850.861 kb on - strand, within Rv0756c at 850.985 kb on - strand, within Rv0756c at 851.055 kb on + strand, within Rv0756c at 851.055 kb on + strand, within Rv0756c at 851.241 kb on + strand, within Rv0756c at 851.242 kb on - strand, within Rv0756c at 851.478 kb on - strand at 851.577 kb on - strand at 851.959 kb on + strand, within Rv0757 at 851.960 kb on - strand, within Rv0757 at 851.968 kb on + strand, within Rv0757 at 852.049 kb on - strand, within Rv0757 at 852.266 kb on - strand, within Rv0757 at 852.359 kb on + strand at 852.359 kb on + strand at 852.363 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM remove 849,824 - Rv0755c 0.89 +0.7 849,966 + -0.1 849,991 + -0.4 849,991 + +0.1 849,992 - +0.1 850,084 + -0.7 850,085 - -0.3 850,088 + +0.0 850,088 + -0.2 850,088 + +0.6 850,089 - -0.4 850,089 - +0.3 850,089 - +0.4 850,115 + -0.3 850,343 + +1.8 850,344 - -0.5 850,344 - +0.0 850,344 - +0.1 850,345 + +0.2 850,345 + +0.7 850,345 + +0.2 850,345 + -0.3 850,346 - -0.2 850,346 - -1.3 850,346 - +0.4 850,346 - -0.5 850,346 - +0.1 850,346 - -0.6 850,346 - -2.3 850,346 - -0.5 850,346 - +0.1 850,369 + Rv0755A 0.15 -1.2 850,369 + Rv0755A 0.15 -1.6 850,369 + Rv0755A 0.15 +0.4 850,395 - Rv0755A 0.28 -0.6 850,410 + Rv0755A 0.37 -0.6 850,410 + Rv0755A 0.37 +0.1 850,410 + Rv0755A 0.37 -0.6 850,411 - Rv0755A 0.37 +0.4 850,497 - Rv0755A 0.83 +0.0 850,625 + +1.4 850,628 + -1.1 850,628 + +0.2 850,628 + +0.1 850,629 - +0.6 850,629 - -1.0 850,629 - -0.5 850,860 + Rv0756c 0.16 -2.0 850,860 + Rv0756c 0.16 +0.7 850,861 - Rv0756c 0.17 -0.1 850,985 - Rv0756c 0.34 -0.0 851,055 + Rv0756c 0.43 +1.0 851,055 + Rv0756c 0.43 +0.2 851,241 + Rv0756c 0.69 -2.0 851,242 - Rv0756c 0.69 +1.5 851,478 - +1.7 851,577 - +1.5 851,959 + Rv0757 0.47 +3.4 851,960 - Rv0757 0.47 +5.2 851,968 + Rv0757 0.48 +0.5 852,049 - Rv0757 0.59 +1.4 852,266 - Rv0757 0.88 +2.6 852,359 + -0.1 852,359 + +1.6 852,363 + -0.2
Or see this region's nucleotide sequence