Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0670

Experiment: 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0669c and Rv0670 are separated by 194 nucleotidesRv0670 and Rv0671 are separated by 31 nucleotidesRv0671 and Rv0672 are separated by 59 nucleotides Rv0669c: Rv0669c - Possible hydrolase, at 767,684 to 769,597 Rv0669c Rv0670: Rv0670 - Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase), at 769,792 to 770,550 Rv0670 Rv0671: Rv0671 - Possible conserved lipoprotein LpqP, at 770,582 to 771,424 Rv0671 Rv0672: Rv0672 - Probable acyl-CoA dehydrogenase FadE8, at 771,484 to 773,112 Rv0672 Position (kb) 769 770 771Strain fitness (log2 ratio) -2 -1 0 1 2 3 4at 768.892 kb on - strand, within Rv0669cat 768.924 kb on + strand, within Rv0669cat 768.925 kb on - strand, within Rv0669cat 768.925 kb on - strand, within Rv0669cat 768.983 kb on - strand, within Rv0669cat 769.036 kb on + strand, within Rv0669cat 769.051 kb on + strand, within Rv0669cat 769.051 kb on + strand, within Rv0669cat 769.051 kb on + strand, within Rv0669cat 769.270 kb on - strand, within Rv0669cat 769.270 kb on - strand, within Rv0669cat 769.345 kb on - strand, within Rv0669cat 769.348 kb on + strand, within Rv0669cat 769.357 kb on - strand, within Rv0669cat 769.586 kb on + strandat 769.586 kb on + strandat 769.664 kb on - strandat 769.706 kb on - strandat 769.781 kb on - strandat 769.860 kb on - strandat 769.951 kb on + strand, within Rv0670at 769.951 kb on + strand, within Rv0670at 769.951 kb on + strand, within Rv0670at 769.951 kb on + strand, within Rv0670at 769.952 kb on - strand, within Rv0670at 769.952 kb on - strand, within Rv0670at 770.171 kb on - strand, within Rv0670at 770.341 kb on - strand, within Rv0670at 770.570 kb on + strandat 770.571 kb on - strandat 770.582 kb on - strandat 770.582 kb on - strandat 770.582 kb on - strandat 770.582 kb on - strandat 770.601 kb on + strandat 770.727 kb on - strand, within Rv0671at 770.728 kb on + strand, within Rv0671at 770.728 kb on + strand, within Rv0671at 770.729 kb on - strand, within Rv0671at 770.729 kb on - strand, within Rv0671at 770.729 kb on - strand, within Rv0671at 770.813 kb on + strand, within Rv0671at 771.005 kb on + strand, within Rv0671at 771.492 kb on + strandat 771.493 kb on - strandat 771.532 kb on + strandat 771.533 kb on - strandat 771.533 kb on - strandat 771.533 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM
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768,892 - Rv0669c 0.63 +0.5
768,924 + Rv0669c 0.65 -0.3
768,925 - Rv0669c 0.65 -0.2
768,925 - Rv0669c 0.65 -0.2
768,983 - Rv0669c 0.68 +0.2
769,036 + Rv0669c 0.71 -0.4
769,051 + Rv0669c 0.71 +0.0
769,051 + Rv0669c 0.71 -0.9
769,051 + Rv0669c 0.71 +0.2
769,270 - Rv0669c 0.83 -0.5
769,270 - Rv0669c 0.83 -0.3
769,345 - Rv0669c 0.87 -0.5
769,348 + Rv0669c 0.87 -0.5
769,357 - Rv0669c 0.87 -0.2
769,586 + +0.0
769,586 + -0.3
769,664 - +3.8
769,706 - -0.4
769,781 - -1.0
769,860 - -0.0
769,951 + Rv0670 0.21 +1.2
769,951 + Rv0670 0.21 +0.2
769,951 + Rv0670 0.21 +0.7
769,951 + Rv0670 0.21 +0.1
769,952 - Rv0670 0.21 +0.1
769,952 - Rv0670 0.21 -1.3
770,171 - Rv0670 0.50 +0.2
770,341 - Rv0670 0.72 +0.2
770,570 + -0.0
770,571 - -1.7
770,582 - +0.0
770,582 - +0.1
770,582 - -0.1
770,582 - +2.4
770,601 + +0.2
770,727 - Rv0671 0.17 -0.3
770,728 + Rv0671 0.17 -0.1
770,728 + Rv0671 0.17 +0.1
770,729 - Rv0671 0.17 -0.2
770,729 - Rv0671 0.17 -0.9
770,729 - Rv0671 0.17 -0.5
770,813 + Rv0671 0.27 -0.9
771,005 + Rv0671 0.50 +0.4
771,492 + +0.3
771,493 - -2.4
771,532 + -0.1
771,533 - +0.6
771,533 - -0.3
771,533 - -0.2

Or see this region's nucleotide sequence