Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1975

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1972 and Rv1973 overlap by 4 nucleotidesRv1973 and Rv1974 are separated by 12 nucleotidesRv1974 and Rv1975 are separated by 15 nucleotidesRv1975 and Rv1976c are separated by 126 nucleotides Rv1972: Rv1972 - Probable conserved Mce associated membrane protein, at 2,216,592 to 2,217,167 Rv1972 Rv1973: Rv1973 - Possible conserved Mce associated membrane protein, at 2,217,164 to 2,217,646 Rv1973 Rv1974: Rv1974 - Probable conserved membrane protein, at 2,217,659 to 2,218,036 Rv1974 Rv1975: Rv1975 - Conserved hypothetical protein, at 2,218,052 to 2,218,717 Rv1975 Rv1976c: Rv1976c - Conserved hypothetical protein, at 2,218,844 to 2,219,251 Rv1976c Position (kb) 2218 2219Strain fitness (log2 ratio) -2 -1 0 1 2at 2217.332 kb on + strand, within Rv1973at 2217.405 kb on - strand, within Rv1973at 2217.779 kb on + strand, within Rv1974at 2217.842 kb on + strand, within Rv1974at 2217.843 kb on - strand, within Rv1974at 2217.947 kb on + strand, within Rv1974at 2217.947 kb on + strand, within Rv1974at 2217.947 kb on + strand, within Rv1974at 2218.040 kb on - strandat 2218.172 kb on + strand, within Rv1975at 2218.228 kb on - strand, within Rv1975at 2218.404 kb on + strand, within Rv1975at 2218.405 kb on - strand, within Rv1975at 2218.415 kb on + strand, within Rv1975at 2218.415 kb on + strand, within Rv1975at 2218.415 kb on + strand, within Rv1975at 2218.418 kb on + strand, within Rv1975at 2218.418 kb on + strand, within Rv1975at 2218.418 kb on + strand, within Rv1975at 2218.419 kb on - strand, within Rv1975at 2218.564 kb on - strand, within Rv1975at 2218.606 kb on + strand, within Rv1975at 2218.625 kb on + strand, within Rv1975at 2218.779 kb on - strandat 2219.230 kb on + strandat 2219.230 kb on + strandat 2219.230 kb on + strandat 2219.231 kb on - strandat 2219.315 kb on + strandat 2219.316 kb on - strandat 2219.410 kb on - strandat 2219.547 kb on - strandat 2219.547 kb on - strandat 2219.567 kb on - strandat 2219.567 kb on - strandat 2219.621 kb on - strandat 2219.621 kb on - strandat 2219.644 kb on + strandat 2219.645 kb on - strandat 2219.645 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,217,332 + Rv1973 0.35 -0.4
2,217,405 - Rv1973 0.50 -0.6
2,217,779 + Rv1974 0.32 +0.9
2,217,842 + Rv1974 0.48 +2.5
2,217,843 - Rv1974 0.49 +0.5
2,217,947 + Rv1974 0.76 +1.2
2,217,947 + Rv1974 0.76 -0.9
2,217,947 + Rv1974 0.76 +0.6
2,218,040 - -0.9
2,218,172 + Rv1975 0.18 +0.1
2,218,228 - Rv1975 0.26 +0.4
2,218,404 + Rv1975 0.53 -0.1
2,218,405 - Rv1975 0.53 +0.1
2,218,415 + Rv1975 0.55 +0.7
2,218,415 + Rv1975 0.55 -1.8
2,218,415 + Rv1975 0.55 -0.4
2,218,418 + Rv1975 0.55 +1.5
2,218,418 + Rv1975 0.55 +1.1
2,218,418 + Rv1975 0.55 +0.5
2,218,419 - Rv1975 0.55 +0.3
2,218,564 - Rv1975 0.77 -0.1
2,218,606 + Rv1975 0.83 -0.0
2,218,625 + Rv1975 0.86 -0.7
2,218,779 - +1.8
2,219,230 + -0.3
2,219,230 + -0.1
2,219,230 + -0.1
2,219,231 - +0.7
2,219,315 + +2.6
2,219,316 - +0.5
2,219,410 - -0.1
2,219,547 - -1.3
2,219,547 - -0.1
2,219,567 - +0.3
2,219,567 - -1.1
2,219,621 - +0.1
2,219,621 - -1.1
2,219,644 + +1.5
2,219,645 - +0.1
2,219,645 - +0.6

Or see this region's nucleotide sequence