Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1268c

Experiment: 7H9 with Vancomycin Hydrochloride from Streptomyces orientalis 0.012 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1267c and Rv1268c are separated by 310 nucleotidesRv1268c and Rv1269c are separated by 222 nucleotidesRv1269c and Rv1270c are separated by 60 nucleotides Rv1267c: Rv1267c - Probable transcriptional regulatory protein EmbR, at 1,416,181 to 1,417,347 Rv1267c Rv1268c: Rv1268c - Hypothetical protein, at 1,417,658 to 1,418,356 Rv1268c Rv1269c: Rv1269c - Conserved probable secreted protein, at 1,418,579 to 1,418,953 Rv1269c Rv1270c: Rv1270c - Possible lipoprotein LprA, at 1,419,014 to 1,419,748 Rv1270c Position (kb) 1417 1418 1419Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 1416.666 kb on - strand, within Rv1267cat 1416.701 kb on + strand, within Rv1267cat 1416.702 kb on - strand, within Rv1267cat 1416.702 kb on - strand, within Rv1267cat 1416.847 kb on + strand, within Rv1267cat 1417.107 kb on + strand, within Rv1267cat 1417.124 kb on + strand, within Rv1267cat 1417.124 kb on + strand, within Rv1267cat 1417.125 kb on - strand, within Rv1267cat 1417.231 kb on + strandat 1417.385 kb on + strandat 1417.386 kb on - strandat 1417.412 kb on - strandat 1417.465 kb on + strandat 1418.012 kb on + strand, within Rv1268cat 1418.073 kb on + strand, within Rv1268cat 1418.074 kb on - strand, within Rv1268cat 1418.244 kb on + strand, within Rv1268cat 1418.244 kb on + strand, within Rv1268cat 1418.244 kb on + strand, within Rv1268cat 1418.245 kb on - strand, within Rv1268cat 1418.245 kb on - strand, within Rv1268cat 1418.245 kb on - strand, within Rv1268cat 1418.245 kb on - strand, within Rv1268cat 1418.380 kb on + strandat 1418.427 kb on + strandat 1418.433 kb on + strandat 1418.562 kb on + strandat 1418.580 kb on + strandat 1418.580 kb on + strandat 1418.580 kb on + strandat 1418.580 kb on + strandat 1418.581 kb on - strandat 1418.674 kb on - strand, within Rv1269cat 1418.681 kb on - strand, within Rv1269cat 1418.739 kb on + strand, within Rv1269cat 1418.838 kb on + strand, within Rv1269cat 1418.939 kb on - strandat 1419.003 kb on + strandat 1419.339 kb on + strand, within Rv1270c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Vancomycin Hydrochloride from Streptomyces orientalis 0.012 mM
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1,416,666 - Rv1267c 0.42 -0.1
1,416,701 + Rv1267c 0.45 -0.3
1,416,702 - Rv1267c 0.45 -0.8
1,416,702 - Rv1267c 0.45 -0.3
1,416,847 + Rv1267c 0.57 +0.1
1,417,107 + Rv1267c 0.79 -2.5
1,417,124 + Rv1267c 0.81 +0.7
1,417,124 + Rv1267c 0.81 +0.2
1,417,125 - Rv1267c 0.81 -0.1
1,417,231 + -1.0
1,417,385 + -1.0
1,417,386 - -0.5
1,417,412 - -0.5
1,417,465 + +2.0
1,418,012 + Rv1268c 0.51 +0.3
1,418,073 + Rv1268c 0.59 +2.5
1,418,074 - Rv1268c 0.60 -0.8
1,418,244 + Rv1268c 0.84 -0.3
1,418,244 + Rv1268c 0.84 +2.5
1,418,244 + Rv1268c 0.84 +1.0
1,418,245 - Rv1268c 0.84 -1.4
1,418,245 - Rv1268c 0.84 -0.2
1,418,245 - Rv1268c 0.84 +0.3
1,418,245 - Rv1268c 0.84 +1.2
1,418,380 + +0.7
1,418,427 + +1.0
1,418,433 + -0.0
1,418,562 + -0.5
1,418,580 + -0.1
1,418,580 + -0.2
1,418,580 + -3.0
1,418,580 + +0.9
1,418,581 - +0.5
1,418,674 - Rv1269c 0.25 +1.0
1,418,681 - Rv1269c 0.27 +1.0
1,418,739 + Rv1269c 0.43 -0.9
1,418,838 + Rv1269c 0.69 -3.3
1,418,939 - +0.0
1,419,003 + -1.2
1,419,339 + Rv1270c 0.44 -0.4

Or see this region's nucleotide sequence