Experiment: 7H9 with Chlorhexidine diacetate salt 0.0021 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3604c and Rv3605c are separated by 208 nucleotides Rv3605c and Rv3606c overlap by 1 nucleotides Rv3606c and Rv3607c overlap by 4 nucleotides Rv3607c and Rv3608c overlap by 8 nucleotides
Rv3604c: Rv3604c - Probable conserved transmembrane protein rich in alanine and arginine and proline, at 4,046,303 to 4,047,496
Rv3604c
Rv3605c: Rv3605c - Probable conserved secreted protein, at 4,047,705 to 4,048,181
Rv3605c
Rv3606c: Rv3606c - 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase FolK (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase) (HPPK) (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) (PPPK) (2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase) (7,8-dihydro-6-hydroxymethylpterin-diphosphokinase) (6-hydroxymethyl-7,8-dihydropterin diphosphokinase), at 4,048,181 to 4,048,747
Rv3606c
Rv3607c: Rv3607c - Probable dihydroneopterin aldolase FolB (DHNA), at 4,048,744 to 4,049,145
Rv3607c
Rv3608c: Rv3608c - Dihydropteroate synthase 1 FolP (DHPS 1) (dihydropteroate pyrophosphorylase 1) (dihydropteroate diphosphorylase 1), at 4,049,138 to 4,049,980
Rv3608c
Position (kb)
4047
4048
4049 Strain fitness (log2 ratio)
-1
0
1 at 4047.596 kb on + strand at 4047.872 kb on - strand, within Rv3605c at 4047.933 kb on + strand, within Rv3605c at 4048.018 kb on + strand, within Rv3605c at 4048.120 kb on + strand, within Rv3605c at 4048.120 kb on + strand, within Rv3605c at 4048.121 kb on - strand, within Rv3605c at 4048.237 kb on + strand at 4048.769 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Chlorhexidine diacetate salt 0.0021 mM remove 4,047,596 + -0.4 4,047,872 - Rv3605c 0.35 -0.9 4,047,933 + Rv3605c 0.48 -0.7 4,048,018 + Rv3605c 0.66 -0.0 4,048,120 + Rv3605c 0.87 -0.7 4,048,120 + Rv3605c 0.87 -1.4 4,048,121 - Rv3605c 0.87 -1.5 4,048,237 + -0.0 4,048,769 - -0.0
Or see this region's nucleotide sequence