Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2030c

Experiment: 7H9 with Chlorhexidine diacetate salt 0.0021 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2029c and Rv2030c are separated by 16 nucleotidesRv2030c and Rv2031c are separated by 11 nucleotidesRv2031c and Rv2032 are separated by 196 nucleotides Rv2029c: Rv2029c - 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase), at 2,275,405 to 2,276,424 Rv2029c Rv2030c: Rv2030c - Conserved protein, at 2,276,441 to 2,278,486 Rv2030c Rv2031c: Rv2031c - Heat shock protein HspX (alpha-crystallin homolog) (14 kDa antigen) (HSP16.3), at 2,278,498 to 2,278,932 Rv2031c Rv2032: Rv2032 - Conserved protein Acg, at 2,279,129 to 2,280,124 Rv2032 Position (kb) 2276 2277 2278 2279Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 2275.445 kb on + strandat 2275.446 kb on - strandat 2275.946 kb on + strand, within Rv2029cat 2275.947 kb on - strand, within Rv2029cat 2276.292 kb on - strand, within Rv2029cat 2276.443 kb on - strandat 2276.667 kb on - strand, within Rv2030cat 2276.918 kb on - strand, within Rv2030cat 2276.918 kb on - strand, within Rv2030cat 2277.057 kb on + strand, within Rv2030cat 2277.057 kb on + strand, within Rv2030cat 2277.058 kb on - strand, within Rv2030cat 2277.099 kb on + strand, within Rv2030cat 2277.099 kb on + strand, within Rv2030cat 2277.100 kb on - strand, within Rv2030cat 2277.231 kb on + strand, within Rv2030cat 2277.231 kb on + strand, within Rv2030cat 2277.231 kb on + strand, within Rv2030cat 2277.322 kb on - strand, within Rv2030cat 2277.372 kb on + strand, within Rv2030cat 2277.373 kb on - strand, within Rv2030cat 2277.537 kb on + strand, within Rv2030cat 2278.584 kb on - strand, within Rv2031cat 2278.593 kb on + strand, within Rv2031cat 2278.594 kb on - strand, within Rv2031cat 2278.728 kb on + strand, within Rv2031cat 2278.728 kb on + strand, within Rv2031cat 2278.775 kb on - strand, within Rv2031cat 2279.107 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Chlorhexidine diacetate salt 0.0021 mM
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2,275,445 + -0.3
2,275,446 - -0.1
2,275,946 + Rv2029c 0.53 -2.9
2,275,947 - Rv2029c 0.53 -0.8
2,276,292 - Rv2029c 0.87 -0.6
2,276,443 - -0.1
2,276,667 - Rv2030c 0.11 +0.1
2,276,918 - Rv2030c 0.23 -0.3
2,276,918 - Rv2030c 0.23 +2.1
2,277,057 + Rv2030c 0.30 +1.4
2,277,057 + Rv2030c 0.30 -2.3
2,277,058 - Rv2030c 0.30 -0.2
2,277,099 + Rv2030c 0.32 +0.4
2,277,099 + Rv2030c 0.32 -0.4
2,277,100 - Rv2030c 0.32 +0.1
2,277,231 + Rv2030c 0.39 +0.1
2,277,231 + Rv2030c 0.39 +0.9
2,277,231 + Rv2030c 0.39 +0.1
2,277,322 - Rv2030c 0.43 -0.3
2,277,372 + Rv2030c 0.46 +0.1
2,277,373 - Rv2030c 0.46 -1.2
2,277,537 + Rv2030c 0.54 +0.1
2,278,584 - Rv2031c 0.20 -0.1
2,278,593 + Rv2031c 0.22 -1.6
2,278,594 - Rv2031c 0.22 +0.2
2,278,728 + Rv2031c 0.53 +0.7
2,278,728 + Rv2031c 0.53 +0.1
2,278,775 - Rv2031c 0.64 -0.4
2,279,107 + +0.5

Or see this region's nucleotide sequence