Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1561

Experiment: 7H9 with Chlorhexidine diacetate salt 0.0021 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1559 and Rv1560 are separated by 37 nucleotidesRv1560 and Rv1561 are separated by 5 nucleotidesRv1561 and Rv1562c are separated by 16 nucleotides Rv1559: Rv1559 - Probable threonine dehydratase IlvA, at 1,763,428 to 1,764,717 Rv1559 Rv1560: Rv1560 - Possible antitoxin VapB11, at 1,764,755 to 1,764,973 Rv1560 Rv1561: Rv1561 - Possible toxin VapC11, at 1,764,979 to 1,765,383 Rv1561 Rv1562c: Rv1562c - Maltooligosyltrehalose trehalohydrolase TreZ, at 1,765,400 to 1,767,142 Rv1562c Position (kb) 1764 1765 1766Strain fitness (log2 ratio) -1 0 1 2at 1764.715 kb on + strandat 1764.769 kb on + strandat 1764.770 kb on - strandat 1765.012 kb on + strandat 1765.280 kb on + strand, within Rv1561at 1765.312 kb on - strand, within Rv1561at 1765.459 kb on + strandat 1765.460 kb on - strandat 1765.719 kb on - strand, within Rv1562cat 1766.113 kb on - strand, within Rv1562cat 1766.113 kb on - strand, within Rv1562cat 1766.166 kb on + strand, within Rv1562c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Chlorhexidine diacetate salt 0.0021 mM
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1,764,715 + -0.2
1,764,769 + +0.9
1,764,770 - +2.0
1,765,012 + +0.1
1,765,280 + Rv1561 0.74 -0.7
1,765,312 - Rv1561 0.82 -1.1
1,765,459 + +0.3
1,765,460 - -1.0
1,765,719 - Rv1562c 0.18 +0.3
1,766,113 - Rv1562c 0.41 -1.0
1,766,113 - Rv1562c 0.41 +1.4
1,766,166 + Rv1562c 0.44 +0.5

Or see this region's nucleotide sequence