Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1354c

Experiment: 7H9 with Chlorhexidine diacetate salt 0.0021 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1352 and Rv1353c are separated by 65 nucleotidesRv1353c and Rv1354c are separated by 19 nucleotidesRv1354c and Rv1355c are separated by 8 nucleotides Rv1352: Rv1352 - Conserved protein, at 1,518,763 to 1,519,134 Rv1352 Rv1353c: Rv1353c - Probable transcriptional regulatory protein, at 1,519,200 to 1,519,985 Rv1353c Rv1354c: Rv1354c - Conserved hypothetical protein, at 1,520,005 to 1,521,876 Rv1354c Rv1355c: Rv1355c - Possible molybdopterin biosynthesis protein MoeY, at 1,521,885 to 1,524,032 Rv1355c Position (kb) 1520 1521 1522Strain fitness (log2 ratio) -1 0 1 2at 1519.050 kb on + strand, within Rv1352at 1519.342 kb on + strand, within Rv1353cat 1519.535 kb on - strand, within Rv1353cat 1519.763 kb on - strand, within Rv1353cat 1519.763 kb on - strand, within Rv1353cat 1519.825 kb on + strand, within Rv1353cat 1520.033 kb on - strandat 1520.182 kb on + strandat 1520.325 kb on + strand, within Rv1354cat 1520.404 kb on + strand, within Rv1354cat 1521.226 kb on + strand, within Rv1354cat 1521.385 kb on - strand, within Rv1354cat 1521.658 kb on + strand, within Rv1354cat 1522.625 kb on - strand, within Rv1355c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Chlorhexidine diacetate salt 0.0021 mM
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1,519,050 + Rv1352 0.77 -0.3
1,519,342 + Rv1353c 0.18 +0.4
1,519,535 - Rv1353c 0.43 +0.0
1,519,763 - Rv1353c 0.72 -0.9
1,519,763 - Rv1353c 0.72 -0.1
1,519,825 + Rv1353c 0.80 -1.0
1,520,033 - -0.8
1,520,182 + +2.3
1,520,325 + Rv1354c 0.17 -0.2
1,520,404 + Rv1354c 0.21 -1.4
1,521,226 + Rv1354c 0.65 -0.8
1,521,385 - Rv1354c 0.74 -0.8
1,521,658 + Rv1354c 0.88 -0.1
1,522,625 - Rv1355c 0.34 +0.5

Or see this region's nucleotide sequence