Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1121

Experiment: 7H9 with Chlorhexidine diacetate salt 0.0021 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1118c and Rv1119c are separated by 32 nucleotidesRv1119c and Rv1120c overlap by 4 nucleotidesRv1120c and Rv1121 are separated by 202 nucleotidesRv1121 and Rv1122 are separated by 21 nucleotides Rv1118c: Rv1118c - Conserved protein, at 1,241,971 to 1,242,831 Rv1118c Rv1119c: Rv1119c - Hypothetical protein, at 1,242,864 to 1,243,013 Rv1119c Rv1120c: Rv1120c - Conserved hypothetical protein, at 1,243,010 to 1,243,504 Rv1120c Rv1121: Rv1121 - Probable glucose-6-phosphate 1-dehydrogenase Zwf1 (G6PD), at 1,243,707 to 1,245,107 Rv1121 Rv1122: Rv1122 - Probable 6-phosphogluconate dehydrogenase,decarboxylating Gnd2, at 1,245,129 to 1,246,151 Rv1122 Position (kb) 1243 1244 1245 1246Strain fitness (log2 ratio) -1 0 1at 1242.799 kb on + strandat 1242.800 kb on - strandat 1242.800 kb on - strandat 1242.862 kb on + strandat 1242.911 kb on - strand, within Rv1119cat 1243.102 kb on + strand, within Rv1120cat 1243.383 kb on - strand, within Rv1120cat 1243.479 kb on - strandat 1243.618 kb on + strandat 1243.619 kb on - strandat 1243.758 kb on - strandat 1244.035 kb on - strand, within Rv1121at 1244.037 kb on + strand, within Rv1121

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Chlorhexidine diacetate salt 0.0021 mM
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1,242,799 + +0.0
1,242,800 - -1.0
1,242,800 - -0.3
1,242,862 + +0.7
1,242,911 - Rv1119c 0.31 -1.2
1,243,102 + Rv1120c 0.19 +0.2
1,243,383 - Rv1120c 0.75 +0.0
1,243,479 - +1.7
1,243,618 + -0.2
1,243,619 - +0.6
1,243,758 - -0.7
1,244,035 - Rv1121 0.23 -1.6
1,244,037 + Rv1121 0.24 +1.0

Or see this region's nucleotide sequence