Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0009

Experiment: 7H9 with Chlorhexidine diacetate salt 0.0021 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0008c and Rv0009 are separated by 156 nucleotidesRv0009 and Rv0010c are separated by 116 nucleotidesRv0010c and Rv0011c are separated by 155 nucleotides Rv0008c: Rv0008c - Possible membrane protein, at 11,874 to 12,311 Rv0008c Rv0009: Rv0009 - Probable iron-regulated peptidyl-prolyl cis-trans isomerase A PpiA (PPIase A) (rotamase A), at 12,468 to 13,016 Rv0009 Rv0010c: Rv0010c - Probable conserved membrane protein, at 13,133 to 13,558 Rv0010c Rv0011c: Rv0011c - Probable conserved transmembrane protein, at 13,714 to 13,995 Rv0011c Position (kb) 12 13 14Strain fitness (log2 ratio) -2 -1 0 1 2at 11.557 kb on - strandat 11.619 kb on - strandat 11.675 kb on + strandat 11.675 kb on + strandat 11.675 kb on + strandat 11.675 kb on + strandat 11.675 kb on + strandat 11.676 kb on - strandat 11.676 kb on - strandat 11.679 kb on + strandat 11.680 kb on - strandat 11.733 kb on + strandat 11.733 kb on + strandat 11.743 kb on + strandat 11.743 kb on + strandat 11.744 kb on - strandat 12.043 kb on - strand, within Rv0008cat 12.353 kb on - strandat 12.492 kb on - strandat 12.512 kb on + strandat 12.621 kb on + strand, within Rv0009at 13.025 kb on + strandat 13.025 kb on + strandat 13.156 kb on - strandat 13.309 kb on + strand, within Rv0010cat 13.309 kb on + strand, within Rv0010cat 13.323 kb on - strand, within Rv0010cat 13.323 kb on - strand, within Rv0010cat 13.325 kb on + strand, within Rv0010cat 13.326 kb on - strand, within Rv0010cat 13.326 kb on - strand, within Rv0010cat 13.369 kb on + strand, within Rv0010cat 13.568 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Chlorhexidine diacetate salt 0.0021 mM
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11,557 - +0.9
11,619 - -2.4
11,675 + +1.0
11,675 + -0.3
11,675 + +0.1
11,675 + +0.0
11,675 + -0.1
11,676 - -0.1
11,676 - -0.1
11,679 + +0.5
11,680 - -0.8
11,733 + +1.0
11,733 + -0.2
11,743 + +0.9
11,743 + -0.1
11,744 - +0.6
12,043 - Rv0008c 0.39 +0.2
12,353 - -0.6
12,492 - -0.2
12,512 + +0.4
12,621 + Rv0009 0.28 -0.6
13,025 + +2.0
13,025 + -0.1
13,156 - -0.1
13,309 + Rv0010c 0.41 +0.1
13,309 + Rv0010c 0.41 +0.4
13,323 - Rv0010c 0.45 -0.4
13,323 - Rv0010c 0.45 -1.7
13,325 + Rv0010c 0.45 +2.0
13,326 - Rv0010c 0.45 +2.0
13,326 - Rv0010c 0.45 -0.2
13,369 + Rv0010c 0.55 -0.7
13,568 - +0.3

Or see this region's nucleotide sequence