Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0536

Experiment: 7H9 with Chlorhexidine diacetate salt 0.0021 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0534c and Rv0535 are separated by 16 nucleotidesRv0535 and Rv0536 overlap by 4 nucleotidesRv0536 and Rv0537c are separated by 9 nucleotides Rv0534c: Rv0534c - 1,4-dihydroxy-2-naphthoate octaprenyltransferase MenA (DHNA-octaprenyltransferase), at 625,562 to 626,440 Rv0534c Rv0535: Rv0535 - Probable 5'-methylthioadenosine phosphorylase Pnp (MTA phosphorylase), at 626,457 to 627,251 Rv0535 Rv0536: Rv0536 - Probable UDP-glucose 4-epimerase GalE3 (galactowaldenase) (UDP-galactose 4-epimerase) (uridine diphosphate galactose 4-epimerase) (uridine diphospho-galactose 4-epimerase), at 627,248 to 628,288 Rv0536 Rv0537c: Rv0537c - Probable integral membrane protein, at 628,298 to 629,731 Rv0537c Position (kb) 627 628 629Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 626.456 kb on + strandat 626.457 kb on - strandat 626.505 kb on + strandat 626.506 kb on - strandat 626.506 kb on - strandat 626.811 kb on + strand, within Rv0535at 626.812 kb on - strand, within Rv0535at 626.812 kb on - strand, within Rv0535at 626.812 kb on - strand, within Rv0535at 627.620 kb on + strand, within Rv0536at 627.620 kb on + strand, within Rv0536at 627.621 kb on - strand, within Rv0536at 627.621 kb on - strand, within Rv0536at 627.774 kb on - strand, within Rv0536at 627.866 kb on + strand, within Rv0536at 627.867 kb on - strand, within Rv0536at 628.163 kb on + strand, within Rv0536at 628.299 kb on + strandat 628.299 kb on + strandat 628.323 kb on + strandat 628.323 kb on + strandat 628.620 kb on - strand, within Rv0537cat 628.740 kb on + strand, within Rv0537cat 628.741 kb on - strand, within Rv0537cat 628.944 kb on + strand, within Rv0537cat 629.095 kb on + strand, within Rv0537cat 629.151 kb on + strand, within Rv0537cat 629.151 kb on + strand, within Rv0537cat 629.151 kb on + strand, within Rv0537cat 629.152 kb on - strand, within Rv0537cat 629.152 kb on - strand, within Rv0537cat 629.227 kb on - strand, within Rv0537cat 629.279 kb on - strand, within Rv0537c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Chlorhexidine diacetate salt 0.0021 mM
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626,456 + -0.8
626,457 - -0.1
626,505 + +0.1
626,506 - -0.7
626,506 - -0.6
626,811 + Rv0535 0.45 -0.5
626,812 - Rv0535 0.45 +0.1
626,812 - Rv0535 0.45 -2.9
626,812 - Rv0535 0.45 +0.7
627,620 + Rv0536 0.36 +0.2
627,620 + Rv0536 0.36 -0.3
627,621 - Rv0536 0.36 +0.0
627,621 - Rv0536 0.36 +0.3
627,774 - Rv0536 0.51 +0.2
627,866 + Rv0536 0.59 +1.3
627,867 - Rv0536 0.59 +2.0
628,163 + Rv0536 0.88 +0.0
628,299 + +0.2
628,299 + -0.4
628,323 + +0.2
628,323 + -0.3
628,620 - Rv0537c 0.22 -0.4
628,740 + Rv0537c 0.31 +1.9
628,741 - Rv0537c 0.31 -0.3
628,944 + Rv0537c 0.45 +0.1
629,095 + Rv0537c 0.56 -0.6
629,151 + Rv0537c 0.59 -0.8
629,151 + Rv0537c 0.59 -0.0
629,151 + Rv0537c 0.59 +1.0
629,152 - Rv0537c 0.60 +0.3
629,152 - Rv0537c 0.60 +0.5
629,227 - Rv0537c 0.65 -0.5
629,279 - Rv0537c 0.68 -0.2

Or see this region's nucleotide sequence