Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0439c

Experiment: 7H9 with Chlorhexidine diacetate salt 0.0021 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0438c and Rv0439c are separated by 18 nucleotidesRv0439c and Rv0440 are separated by 293 nucleotides Rv0438c: Rv0438c - Probable molybdopterin biosynthesis protein MoeA2, at 526,143 to 527,360 Rv0438c Rv0439c: Rv0439c - Probable dehydrogenase/reductase, at 527,379 to 528,314 Rv0439c Rv0440: Rv0440 - 60 kDa chaperonin 2 GroEL2 (protein CPN60-2) (GroEL protein 2) (65 kDa antigen) (heat shock protein 65) (cell wall protein A) (antigen A), at 528,608 to 530,230 Rv0440 Position (kb) 527 528 529Strain fitness (log2 ratio) -1 0 1at 526.558 kb on + strand, within Rv0438cat 526.559 kb on - strand, within Rv0438cat 526.594 kb on + strand, within Rv0438cat 526.595 kb on - strand, within Rv0438cat 526.763 kb on - strand, within Rv0438cat 526.779 kb on + strand, within Rv0438cat 526.780 kb on - strand, within Rv0438cat 527.201 kb on - strand, within Rv0438cat 527.201 kb on - strand, within Rv0438cat 527.201 kb on - strand, within Rv0438cat 527.297 kb on + strandat 527.388 kb on + strandat 527.515 kb on + strand, within Rv0439cat 527.515 kb on + strand, within Rv0439cat 527.518 kb on + strand, within Rv0439cat 527.518 kb on + strand, within Rv0439cat 527.518 kb on + strand, within Rv0439cat 527.519 kb on - strand, within Rv0439cat 527.627 kb on + strand, within Rv0439cat 527.731 kb on + strand, within Rv0439cat 527.731 kb on + strand, within Rv0439cat 527.785 kb on + strand, within Rv0439cat 528.171 kb on + strand, within Rv0439cat 528.171 kb on + strand, within Rv0439cat 528.172 kb on - strand, within Rv0439cat 528.172 kb on - strand, within Rv0439cat 528.172 kb on - strand, within Rv0439cat 528.288 kb on - strandat 528.288 kb on - strandat 528.288 kb on - strandat 528.288 kb on - strandat 528.325 kb on + strandat 528.325 kb on + strandat 528.326 kb on - strandat 528.326 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Chlorhexidine diacetate salt 0.0021 mM
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526,558 + Rv0438c 0.34 -0.1
526,559 - Rv0438c 0.34 -0.6
526,594 + Rv0438c 0.37 -0.1
526,595 - Rv0438c 0.37 -0.2
526,763 - Rv0438c 0.51 +0.3
526,779 + Rv0438c 0.52 +0.5
526,780 - Rv0438c 0.52 +0.2
527,201 - Rv0438c 0.87 -0.5
527,201 - Rv0438c 0.87 -0.4
527,201 - Rv0438c 0.87 +0.5
527,297 + +0.2
527,388 + -0.4
527,515 + Rv0439c 0.15 +0.4
527,515 + Rv0439c 0.15 +0.2
527,518 + Rv0439c 0.15 -0.2
527,518 + Rv0439c 0.15 -0.6
527,518 + Rv0439c 0.15 -0.2
527,519 - Rv0439c 0.15 +0.9
527,627 + Rv0439c 0.26 -0.2
527,731 + Rv0439c 0.38 +0.5
527,731 + Rv0439c 0.38 +0.2
527,785 + Rv0439c 0.43 -0.4
528,171 + Rv0439c 0.85 -1.0
528,171 + Rv0439c 0.85 -0.1
528,172 - Rv0439c 0.85 +0.6
528,172 - Rv0439c 0.85 -0.9
528,172 - Rv0439c 0.85 -0.6
528,288 - -0.4
528,288 - -0.7
528,288 - -0.5
528,288 - +0.6
528,325 + -1.1
528,325 + -0.5
528,326 - -0.0
528,326 - -0.1

Or see this region's nucleotide sequence