Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0757

Experiment: 7H9 with Tetrazolium violet 0.065 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntGFF789 and Rv0756c are separated by 27 nucleotidesRv0756c and Rv0757 are separated by 141 nucleotidesRv0757 and Rv0758 are separated by 44 nucleotides GFF789 - tRNA-Thr, at 850,642 to 850,713 GFF789 Rv0756c: Rv0756c - Unknown protein, at 850,741 to 851,466 Rv0756c Rv0757: Rv0757 - Possible two component system response transcriptional positive regulator PhoP, at 851,608 to 852,351 Rv0757 Rv0758: Rv0758 - Possible two component system response sensor kinase membrane associated PhoR, at 852,396 to 853,853 Rv0758 Position (kb) 851 852 853Strain fitness (log2 ratio) -2 -1 0 1 2at 850.625 kb on + strandat 850.628 kb on + strandat 850.628 kb on + strandat 850.628 kb on + strandat 850.629 kb on - strandat 850.629 kb on - strandat 850.629 kb on - strandat 850.860 kb on + strand, within Rv0756cat 850.860 kb on + strand, within Rv0756cat 850.861 kb on - strand, within Rv0756cat 850.985 kb on - strand, within Rv0756cat 851.055 kb on + strand, within Rv0756cat 851.055 kb on + strand, within Rv0756cat 851.241 kb on + strand, within Rv0756cat 851.242 kb on - strand, within Rv0756cat 851.478 kb on - strandat 851.577 kb on - strandat 851.959 kb on + strand, within Rv0757at 851.960 kb on - strand, within Rv0757at 851.968 kb on + strand, within Rv0757at 852.049 kb on - strand, within Rv0757at 852.266 kb on - strand, within Rv0757at 852.359 kb on + strandat 852.359 kb on + strandat 852.363 kb on + strandat 852.601 kb on - strand, within Rv0758at 852.612 kb on - strand, within Rv0758at 852.640 kb on - strand, within Rv0758at 852.640 kb on - strand, within Rv0758at 852.672 kb on + strand, within Rv0758at 852.775 kb on + strand, within Rv0758

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Tetrazolium violet 0.065 mM
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850,625 + -0.1
850,628 + -0.1
850,628 + +0.2
850,628 + +0.1
850,629 - -0.1
850,629 - +0.4
850,629 - -0.1
850,860 + Rv0756c 0.16 -1.9
850,860 + Rv0756c 0.16 -0.6
850,861 - Rv0756c 0.17 -0.1
850,985 - Rv0756c 0.34 -0.1
851,055 + Rv0756c 0.43 +2.1
851,055 + Rv0756c 0.43 -0.0
851,241 + Rv0756c 0.69 -1.2
851,242 - Rv0756c 0.69 +0.4
851,478 - -1.3
851,577 - +0.4
851,959 + Rv0757 0.47 +0.9
851,960 - Rv0757 0.47 -0.5
851,968 + Rv0757 0.48 -2.0
852,049 - Rv0757 0.59 -1.1
852,266 - Rv0757 0.88 -1.5
852,359 + +0.1
852,359 + +0.5
852,363 + +0.7
852,601 - Rv0758 0.14 -0.5
852,612 - Rv0758 0.15 -1.1
852,640 - Rv0758 0.17 -1.8
852,640 - Rv0758 0.17 +0.9
852,672 + Rv0758 0.19 +0.4
852,775 + Rv0758 0.26 -0.1

Or see this region's nucleotide sequence