Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0294

Experiment: 7H9 with Tetrazolium violet 0.065 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0293c and Rv0294 are separated by 106 nucleotidesRv0294 and Rv0295c overlap by 12 nucleotidesRv0295c and Rv0296c are separated by 9 nucleotides Rv0293c: Rv0293c - Conserved protein, at 356,862 to 358,064 Rv0293c Rv0294: Rv0294 - Probable trans-aconitate methyltransferase Tam, at 358,171 to 358,956 Rv0294 Rv0295c: Rv0295c - Conserved protein, at 358,945 to 359,748 Rv0295c Rv0296c: Rv0296c - Probable sulfatase, at 359,758 to 361,155 Rv0296c Position (kb) 358 359Strain fitness (log2 ratio) -2 -1 0 1 2at 357.259 kb on + strand, within Rv0293cat 357.275 kb on + strand, within Rv0293cat 357.275 kb on + strand, within Rv0293cat 357.276 kb on - strand, within Rv0293cat 357.340 kb on + strand, within Rv0293cat 357.340 kb on + strand, within Rv0293cat 357.452 kb on - strand, within Rv0293cat 357.481 kb on + strand, within Rv0293cat 357.517 kb on + strand, within Rv0293cat 357.518 kb on - strand, within Rv0293cat 357.554 kb on + strand, within Rv0293cat 357.555 kb on - strand, within Rv0293cat 357.844 kb on - strand, within Rv0293cat 358.168 kb on + strandat 358.168 kb on + strandat 358.168 kb on + strandat 358.168 kb on + strandat 358.168 kb on + strandat 358.169 kb on - strandat 358.169 kb on - strandat 358.169 kb on - strandat 358.169 kb on - strandat 358.307 kb on - strand, within Rv0294at 358.619 kb on + strand, within Rv0294at 358.726 kb on + strand, within Rv0294at 358.727 kb on - strand, within Rv0294at 358.884 kb on + strandat 358.885 kb on - strandat 358.955 kb on - strandat 359.108 kb on - strand, within Rv0295cat 359.533 kb on - strand, within Rv0295cat 359.533 kb on - strand, within Rv0295cat 359.623 kb on - strand, within Rv0295cat 359.631 kb on - strand, within Rv0295cat 359.726 kb on + strandat 359.726 kb on + strandat 359.726 kb on + strandat 359.759 kb on + strandat 359.838 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Tetrazolium violet 0.065 mM
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357,259 + Rv0293c 0.33 -0.5
357,275 + Rv0293c 0.34 -1.1
357,275 + Rv0293c 0.34 +1.0
357,276 - Rv0293c 0.34 -0.2
357,340 + Rv0293c 0.40 -0.5
357,340 + Rv0293c 0.40 -1.2
357,452 - Rv0293c 0.49 -0.5
357,481 + Rv0293c 0.51 +1.8
357,517 + Rv0293c 0.54 +1.4
357,518 - Rv0293c 0.55 -0.0
357,554 + Rv0293c 0.58 +0.3
357,555 - Rv0293c 0.58 -0.2
357,844 - Rv0293c 0.82 +0.6
358,168 + -0.4
358,168 + +0.8
358,168 + -0.5
358,168 + -0.1
358,168 + +0.1
358,169 - +0.3
358,169 - -0.2
358,169 - +0.1
358,169 - -0.3
358,307 - Rv0294 0.17 -1.8
358,619 + Rv0294 0.57 -0.4
358,726 + Rv0294 0.71 -0.4
358,727 - Rv0294 0.71 -2.3
358,884 + -1.5
358,885 - -0.1
358,955 - +0.2
359,108 - Rv0295c 0.20 -0.5
359,533 - Rv0295c 0.73 +0.8
359,533 - Rv0295c 0.73 +0.4
359,623 - Rv0295c 0.84 -0.2
359,631 - Rv0295c 0.85 +0.3
359,726 + -0.5
359,726 + -0.0
359,726 + +0.4
359,759 + -0.3
359,838 - -0.7

Or see this region's nucleotide sequence