Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2627c

Experiment: 7H9 with Tetrazolium violet 0.065 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2626c and Rv2627c are separated by 513 nucleotidesRv2627c and Rv2628 are separated by 309 nucleotides Rv2626c: Rv2626c - Hypoxic response protein 1 Hrp1, at 2,952,562 to 2,952,993 Rv2626c Rv2627c: Rv2627c - Conserved protein, at 2,953,507 to 2,954,748 Rv2627c Rv2628: Rv2628 - Hypothetical protein, at 2,955,058 to 2,955,420 Rv2628 Position (kb) 2953 2954 2955Strain fitness (log2 ratio) -3 -2 -1 0 1at 2952.759 kb on - strand, within Rv2626cat 2952.914 kb on + strand, within Rv2626cat 2952.914 kb on + strand, within Rv2626cat 2953.020 kb on - strandat 2953.066 kb on - strandat 2953.106 kb on - strandat 2953.201 kb on + strandat 2953.201 kb on + strandat 2953.373 kb on + strandat 2953.746 kb on + strand, within Rv2627cat 2953.925 kb on + strand, within Rv2627cat 2953.926 kb on - strand, within Rv2627cat 2954.207 kb on - strand, within Rv2627cat 2954.246 kb on - strand, within Rv2627cat 2954.256 kb on - strand, within Rv2627cat 2954.276 kb on + strand, within Rv2627cat 2954.277 kb on - strand, within Rv2627cat 2954.577 kb on + strand, within Rv2627cat 2954.646 kb on - strandat 2954.791 kb on + strandat 2954.791 kb on + strandat 2955.418 kb on + strandat 2955.430 kb on - strandat 2955.430 kb on - strandat 2955.483 kb on + strandat 2955.483 kb on + strandat 2955.581 kb on - strandat 2955.589 kb on - strandat 2955.643 kb on - strandat 2955.726 kb on + strandat 2955.727 kb on - strandat 2955.739 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Tetrazolium violet 0.065 mM
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2,952,759 - Rv2626c 0.46 -0.1
2,952,914 + Rv2626c 0.81 +0.4
2,952,914 + Rv2626c 0.81 -0.5
2,953,020 - +1.2
2,953,066 - -0.3
2,953,106 - -0.5
2,953,201 + -0.1
2,953,201 + +0.6
2,953,373 + -0.7
2,953,746 + Rv2627c 0.19 -0.3
2,953,925 + Rv2627c 0.34 -0.9
2,953,926 - Rv2627c 0.34 -0.5
2,954,207 - Rv2627c 0.56 -1.1
2,954,246 - Rv2627c 0.60 -1.3
2,954,256 - Rv2627c 0.60 -0.0
2,954,276 + Rv2627c 0.62 +0.0
2,954,277 - Rv2627c 0.62 -1.0
2,954,577 + Rv2627c 0.86 +0.2
2,954,646 - -2.8
2,954,791 + +0.7
2,954,791 + -0.9
2,955,418 + -0.2
2,955,430 - -0.3
2,955,430 - +0.4
2,955,483 + -1.1
2,955,483 + -0.3
2,955,581 - -1.2
2,955,589 - -0.2
2,955,643 - -0.4
2,955,726 + -0.1
2,955,727 - -0.6
2,955,739 - +1.1

Or see this region's nucleotide sequence