Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1496

Experiment: 7H9 with Tetrazolium violet 0.065 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1493 and Rv1494 are separated by 13 nucleotidesRv1494 and Rv1495 overlap by 4 nucleotidesRv1495 and Rv1496 overlap by 4 nucleotidesRv1496 and Rv1497 are separated by 52 nucleotides Rv1493: Rv1493 - Probable methylmalonyl-CoA mutase large subunit MutB (MCM), at 1,684,005 to 1,686,257 Rv1493 Rv1494: Rv1494 - Possible antitoxin MazE4, at 1,686,271 to 1,686,573 Rv1494 Rv1495: Rv1495 - Possible toxin MazF4, at 1,686,570 to 1,686,887 Rv1495 Rv1496: Rv1496 - Possible transport system kinase, at 1,686,884 to 1,687,888 Rv1496 Rv1497: Rv1497 - Probable esterase LipL, at 1,687,941 to 1,689,230 Rv1497 Position (kb) 1686 1687 1688Strain fitness (log2 ratio) -1 0 1at 1686.243 kb on + strandat 1686.243 kb on + strandat 1686.371 kb on - strand, within Rv1494at 1686.440 kb on + strand, within Rv1494at 1686.466 kb on + strand, within Rv1494at 1686.497 kb on - strand, within Rv1494at 1686.502 kb on + strand, within Rv1494at 1686.503 kb on - strand, within Rv1494at 1686.713 kb on - strand, within Rv1495at 1686.875 kb on - strandat 1687.207 kb on + strand, within Rv1496at 1687.207 kb on + strand, within Rv1496at 1687.568 kb on + strand, within Rv1496at 1687.568 kb on + strand, within Rv1496at 1687.569 kb on - strand, within Rv1496at 1687.857 kb on + strandat 1687.882 kb on + strandat 1687.887 kb on - strandat 1687.887 kb on - strandat 1688.106 kb on + strand, within Rv1497at 1688.107 kb on - strand, within Rv1497at 1688.642 kb on + strand, within Rv1497at 1688.642 kb on + strand, within Rv1497at 1688.642 kb on + strand, within Rv1497at 1688.643 kb on - strand, within Rv1497at 1688.643 kb on - strand, within Rv1497at 1688.718 kb on + strand, within Rv1497at 1688.860 kb on + strand, within Rv1497at 1688.860 kb on + strand, within Rv1497at 1688.860 kb on + strand, within Rv1497at 1688.861 kb on - strand, within Rv1497at 1688.861 kb on - strand, within Rv1497

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Tetrazolium violet 0.065 mM
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1,686,243 + -0.1
1,686,243 + -1.0
1,686,371 - Rv1494 0.33 -0.4
1,686,440 + Rv1494 0.56 -0.1
1,686,466 + Rv1494 0.64 +0.1
1,686,497 - Rv1494 0.75 -0.5
1,686,502 + Rv1494 0.76 -0.5
1,686,503 - Rv1494 0.77 +0.8
1,686,713 - Rv1495 0.45 -0.2
1,686,875 - -0.2
1,687,207 + Rv1496 0.32 -0.9
1,687,207 + Rv1496 0.32 -0.4
1,687,568 + Rv1496 0.68 +1.7
1,687,568 + Rv1496 0.68 -0.7
1,687,569 - Rv1496 0.68 +0.3
1,687,857 + -0.1
1,687,882 + +0.9
1,687,887 - -0.5
1,687,887 - +0.1
1,688,106 + Rv1497 0.13 +0.7
1,688,107 - Rv1497 0.13 -0.3
1,688,642 + Rv1497 0.54 +0.7
1,688,642 + Rv1497 0.54 -0.7
1,688,642 + Rv1497 0.54 -0.1
1,688,643 - Rv1497 0.54 -0.1
1,688,643 - Rv1497 0.54 -0.0
1,688,718 + Rv1497 0.60 -0.1
1,688,860 + Rv1497 0.71 +0.3
1,688,860 + Rv1497 0.71 -0.2
1,688,860 + Rv1497 0.71 +0.1
1,688,861 - Rv1497 0.71 +0.2
1,688,861 - Rv1497 0.71 +0.2

Or see this region's nucleotide sequence