Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1170

Experiment: 7H9 with Tetrazolium violet 0.065 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1168c and Rv1169c are separated by 17 nucleotidesRv1169c and Rv1170 are separated by 179 nucleotidesRv1170 and Rv1171 are separated by 91 nucleotidesRv1171 and Rv1172c are separated by 7 nucleotides Rv1168c: Rv1168c - PPE family protein PPE17, at 1,298,764 to 1,299,804 Rv1168c Rv1169c: Rv1169c - PE family protein. Possible lipase LipX., at 1,299,822 to 1,300,124 Rv1169c Rv1170: Rv1170 - N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase), at 1,300,304 to 1,301,215 Rv1170 Rv1171: Rv1171 - Conserved hypothetical protein, at 1,301,307 to 1,301,747 Rv1171 Rv1172c: Rv1172c - PE family protein PE12, at 1,301,755 to 1,302,681 Rv1172c Position (kb) 1300 1301 1302Strain fitness (log2 ratio) -1 0 1 2 3 4 5at 1299.353 kb on + strand, within Rv1168cat 1299.387 kb on - strand, within Rv1168cat 1299.395 kb on + strand, within Rv1168cat 1299.396 kb on - strand, within Rv1168cat 1299.692 kb on + strand, within Rv1168cat 1299.736 kb on + strandat 1299.737 kb on - strandat 1299.866 kb on - strand, within Rv1169cat 1299.940 kb on + strand, within Rv1169cat 1299.941 kb on - strand, within Rv1169cat 1299.941 kb on - strand, within Rv1169cat 1300.231 kb on - strandat 1300.293 kb on - strandat 1300.385 kb on + strandat 1300.385 kb on + strandat 1300.386 kb on - strandat 1300.503 kb on - strand, within Rv1170at 1300.709 kb on + strand, within Rv1170at 1300.710 kb on - strand, within Rv1170at 1300.728 kb on - strand, within Rv1170at 1301.120 kb on + strand, within Rv1170at 1301.121 kb on - strand, within Rv1170at 1301.121 kb on - strand, within Rv1170at 1301.213 kb on + strandat 1301.214 kb on - strandat 1301.457 kb on + strand, within Rv1171at 1301.458 kb on - strand, within Rv1171at 1301.458 kb on - strand, within Rv1171at 1301.458 kb on - strand, within Rv1171at 1301.458 kb on - strand, within Rv1171at 1301.459 kb on + strand, within Rv1171at 1301.585 kb on - strand, within Rv1171at 1301.659 kb on - strand, within Rv1171at 1301.874 kb on + strand, within Rv1172cat 1301.966 kb on + strand, within Rv1172cat 1301.967 kb on - strand, within Rv1172cat 1301.967 kb on - strand, within Rv1172cat 1301.992 kb on + strand, within Rv1172cat 1301.993 kb on - strand, within Rv1172cat 1302.002 kb on + strand, within Rv1172cat 1302.003 kb on - strand, within Rv1172cat 1302.072 kb on - strand, within Rv1172c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Tetrazolium violet 0.065 mM
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1,299,353 + Rv1168c 0.57 -1.0
1,299,387 - Rv1168c 0.60 +0.3
1,299,395 + Rv1168c 0.61 -1.3
1,299,396 - Rv1168c 0.61 +0.4
1,299,692 + Rv1168c 0.89 -0.7
1,299,736 + -0.8
1,299,737 - +1.2
1,299,866 - Rv1169c 0.15 +5.1
1,299,940 + Rv1169c 0.39 -0.5
1,299,941 - Rv1169c 0.39 +1.1
1,299,941 - Rv1169c 0.39 -0.2
1,300,231 - -0.7
1,300,293 - -0.1
1,300,385 + -0.8
1,300,385 + -0.4
1,300,386 - -1.1
1,300,503 - Rv1170 0.22 +0.5
1,300,709 + Rv1170 0.44 -0.0
1,300,710 - Rv1170 0.45 +1.2
1,300,728 - Rv1170 0.46 +1.0
1,301,120 + Rv1170 0.89 +0.4
1,301,121 - Rv1170 0.90 +0.2
1,301,121 - Rv1170 0.90 +1.6
1,301,213 + +0.1
1,301,214 - +0.7
1,301,457 + Rv1171 0.34 +1.0
1,301,458 - Rv1171 0.34 -0.5
1,301,458 - Rv1171 0.34 +1.7
1,301,458 - Rv1171 0.34 +0.7
1,301,458 - Rv1171 0.34 -0.4
1,301,459 + Rv1171 0.34 -0.5
1,301,585 - Rv1171 0.63 -0.0
1,301,659 - Rv1171 0.80 -1.5
1,301,874 + Rv1172c 0.13 -0.3
1,301,966 + Rv1172c 0.23 -0.1
1,301,967 - Rv1172c 0.23 +0.5
1,301,967 - Rv1172c 0.23 +0.3
1,301,992 + Rv1172c 0.26 +0.5
1,301,993 - Rv1172c 0.26 -0.8
1,302,002 + Rv1172c 0.27 -0.6
1,302,003 - Rv1172c 0.27 +1.0
1,302,072 - Rv1172c 0.34 -0.7

Or see this region's nucleotide sequence