Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0858c

Experiment: 7H9 with Dibucaine 0.21 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0856 and Rv0857 are separated by 27 nucleotidesRv0857 and Rv0858c overlap by 4 nucleotidesRv0858c and Rv0859 are separated by 156 nucleotides Rv0856: Rv0856 - Conserved hypothetical protein, at 952,825 to 953,229 Rv0856 Rv0857: Rv0857 - Conserved hypothetical protein, at 953,257 to 953,730 Rv0857 Rv0858c: Rv0858c - Probable N-succinyldiaminopimelate aminotransferase DapC (DAP-at), at 953,727 to 954,920 Rv0858c Rv0859: Rv0859 - Possible acyl-CoA thiolase FadA, at 955,077 to 956,288 Rv0859 Position (kb) 953 954 955Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 952.778 kb on - strandat 952.778 kb on - strandat 952.897 kb on + strand, within Rv0856at 952.898 kb on - strand, within Rv0856at 952.898 kb on - strand, within Rv0856at 952.898 kb on - strand, within Rv0856at 952.975 kb on + strand, within Rv0856at 952.975 kb on + strand, within Rv0856at 952.976 kb on - strand, within Rv0856at 952.976 kb on - strand, within Rv0856at 953.047 kb on + strand, within Rv0856at 953.048 kb on - strand, within Rv0856at 953.048 kb on - strand, within Rv0856at 953.048 kb on - strand, within Rv0856at 953.048 kb on - strand, within Rv0856at 953.266 kb on - strandat 953.266 kb on - strandat 953.273 kb on + strandat 953.273 kb on + strandat 953.274 kb on - strandat 953.474 kb on + strand, within Rv0857at 953.554 kb on + strand, within Rv0857at 953.967 kb on + strand, within Rv0858cat 953.984 kb on - strand, within Rv0858cat 954.134 kb on - strand, within Rv0858cat 954.309 kb on + strand, within Rv0858cat 954.320 kb on - strand, within Rv0858cat 954.514 kb on - strand, within Rv0858cat 954.676 kb on + strand, within Rv0858cat 954.752 kb on - strand, within Rv0858cat 954.999 kb on + strandat 955.019 kb on + strandat 955.019 kb on + strandat 955.019 kb on + strandat 955.019 kb on + strandat 955.828 kb on + strand, within Rv0859

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dibucaine 0.21 mM
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952,778 - +0.5
952,778 - +0.7
952,897 + Rv0856 0.18 -1.5
952,898 - Rv0856 0.18 +0.7
952,898 - Rv0856 0.18 +1.0
952,898 - Rv0856 0.18 +0.2
952,975 + Rv0856 0.37 -0.6
952,975 + Rv0856 0.37 +0.1
952,976 - Rv0856 0.37 -0.1
952,976 - Rv0856 0.37 -0.1
953,047 + Rv0856 0.55 +0.6
953,048 - Rv0856 0.55 +0.0
953,048 - Rv0856 0.55 +0.2
953,048 - Rv0856 0.55 -1.1
953,048 - Rv0856 0.55 -0.3
953,266 - -1.6
953,266 - -1.8
953,273 + -3.6
953,273 + -1.2
953,274 - -0.3
953,474 + Rv0857 0.46 -1.9
953,554 + Rv0857 0.63 -1.1
953,967 + Rv0858c 0.20 +0.8
953,984 - Rv0858c 0.22 +0.7
954,134 - Rv0858c 0.34 -0.4
954,309 + Rv0858c 0.49 -0.2
954,320 - Rv0858c 0.50 +1.8
954,514 - Rv0858c 0.66 +0.2
954,676 + Rv0858c 0.79 +0.5
954,752 - Rv0858c 0.86 +0.2
954,999 + -0.3
955,019 + +1.1
955,019 + +0.2
955,019 + -0.5
955,019 + -0.2
955,828 + Rv0859 0.62 +1.6

Or see this region's nucleotide sequence