Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0235c

Experiment: 7H9 with Dibucaine 0.21 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0234c and Rv0235c are separated by 25 nucleotidesRv0235c and Rv0236c are separated by 34 nucleotides Rv0234c: Rv0234c - Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1, at 279,605 to 281,140 Rv0234c Rv0235c: Rv0235c - Probable conserved transmembrane protein, at 281,166 to 282,614 Rv0235c Rv0236c: Rv0236c - Possible arabinofuranosyltransferase AftD, at 282,649 to 286,851 Rv0236c Position (kb) 281 282 283Strain fitness (log2 ratio) -1 0 1at 280.627 kb on - strand, within Rv0234cat 280.987 kb on - strandat 281.036 kb on - strandat 281.155 kb on - strandat 282.064 kb on + strand, within Rv0235cat 282.065 kb on - strand, within Rv0235cat 282.065 kb on - strand, within Rv0235cat 282.067 kb on + strand, within Rv0235cat 282.067 kb on + strand, within Rv0235cat 282.254 kb on - strand, within Rv0235cat 282.544 kb on + strandat 282.589 kb on + strandat 282.589 kb on + strandat 282.650 kb on + strandat 282.650 kb on + strandat 282.650 kb on + strandat 282.651 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dibucaine 0.21 mM
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280,627 - Rv0234c 0.67 +0.6
280,987 - -0.5
281,036 - +1.6
281,155 - -0.1
282,064 + Rv0235c 0.62 -0.4
282,065 - Rv0235c 0.62 +1.3
282,065 - Rv0235c 0.62 -0.7
282,067 + Rv0235c 0.62 -1.0
282,067 + Rv0235c 0.62 -0.2
282,254 - Rv0235c 0.75 -1.6
282,544 + -0.4
282,589 + -0.2
282,589 + +0.2
282,650 + +0.5
282,650 + -0.2
282,650 + +0.3
282,651 - -0.9

Or see this region's nucleotide sequence