Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3633

Experiment: 7H9 with Dibucaine 0.21 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3631 and Rv3632 overlap by 4 nucleotidesRv3632 and Rv3633 are separated by 210 nucleotidesRv3633 and Rv3634c are separated by 0 nucleotidesRv3634c and Rv3635 are separated by 22 nucleotides Rv3631: Rv3631 - Possible transferase (possibly glycosyltransferase), at 4,070,514 to 4,071,239 Rv3631 Rv3632: Rv3632 - Possible conserved membrane protein, at 4,071,236 to 4,071,580 Rv3632 Rv3633: Rv3633 - Conserved protein, at 4,071,791 to 4,072,666 Rv3633 Rv3634c: Rv3634c - UDP-glucose 4-epimerase GalE1 (galactowaldenase) (UDP-galactose 4-epimerase) (uridine diphosphate galactose 4-epimerase) (uridine diphospho-galactose 4-epimerase), at 4,072,667 to 4,073,611 Rv3634c Rv3635: Rv3635 - Probable conserved transmembrane protein, at 4,073,634 to 4,075,409 Rv3635 Position (kb) 4071 4072 4073Strain fitness (log2 ratio) -1 0 1 2at 4071.288 kb on - strand, within Rv3632at 4071.341 kb on + strand, within Rv3632at 4071.369 kb on - strand, within Rv3632at 4071.369 kb on - strand, within Rv3632at 4071.488 kb on + strand, within Rv3632at 4071.488 kb on + strand, within Rv3632at 4071.489 kb on - strand, within Rv3632at 4071.489 kb on - strand, within Rv3632at 4071.578 kb on + strandat 4071.668 kb on - strandat 4071.677 kb on - strandat 4071.682 kb on + strandat 4071.710 kb on + strandat 4071.710 kb on + strandat 4071.772 kb on + strandat 4071.846 kb on - strandat 4071.853 kb on - strandat 4071.891 kb on - strand, within Rv3633at 4071.891 kb on - strand, within Rv3633at 4071.894 kb on + strand, within Rv3633at 4072.129 kb on + strand, within Rv3633at 4072.129 kb on + strand, within Rv3633at 4072.525 kb on - strand, within Rv3633at 4072.671 kb on + strandat 4073.648 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dibucaine 0.21 mM
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4,071,288 - Rv3632 0.15 +2.0
4,071,341 + Rv3632 0.30 -0.1
4,071,369 - Rv3632 0.39 +1.8
4,071,369 - Rv3632 0.39 -1.3
4,071,488 + Rv3632 0.73 +1.3
4,071,488 + Rv3632 0.73 -0.8
4,071,489 - Rv3632 0.73 -0.0
4,071,489 - Rv3632 0.73 -0.8
4,071,578 + -1.3
4,071,668 - -0.1
4,071,677 - +0.9
4,071,682 + +1.1
4,071,710 + +0.0
4,071,710 + -0.1
4,071,772 + -0.5
4,071,846 - +0.5
4,071,853 - -0.1
4,071,891 - Rv3633 0.11 +0.8
4,071,891 - Rv3633 0.11 -0.8
4,071,894 + Rv3633 0.12 -1.0
4,072,129 + Rv3633 0.39 -1.0
4,072,129 + Rv3633 0.39 +0.1
4,072,525 - Rv3633 0.84 +0.2
4,072,671 + -0.1
4,073,648 + +0.1

Or see this region's nucleotide sequence