Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3475

Experiment: 7H9 with Dibucaine 0.21 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3473c and Rv3474 are separated by 96 nucleotidesRv3474 and Rv3475 overlap by 52 nucleotidesRv3475 and Rv3476c are separated by 279 nucleotides Rv3473c: Rv3473c - Possible peroxidase BpoA (non-haem peroxidase), at 3,889,948 to 3,890,733 Rv3473c Rv3474: Rv3474 - Possible transposase for insertion element IS6110 (fragment), at 3,890,830 to 3,891,156 Rv3474 Rv3475: Rv3475 - Possible transposase for insertion element IS6110 [second part], at 3,891,105 to 3,892,091 Rv3475 Rv3476c: Rv3476c - Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter), at 3,892,371 to 3,893,720 Rv3476c Position (kb) 3891 3892 3893Strain fitness (log2 ratio) -2 -1 0 1 2at 3890.200 kb on + strand, within Rv3473cat 3890.201 kb on - strand, within Rv3473cat 3890.220 kb on + strand, within Rv3473cat 3890.221 kb on - strand, within Rv3473cat 3890.253 kb on - strand, within Rv3473cat 3890.253 kb on - strand, within Rv3473cat 3890.327 kb on + strand, within Rv3473cat 3890.327 kb on + strand, within Rv3473cat 3890.328 kb on - strand, within Rv3473cat 3892.223 kb on + strandat 3892.223 kb on + strandat 3892.224 kb on - strandat 3892.356 kb on - strandat 3892.356 kb on - strandat 3892.372 kb on + strandat 3892.372 kb on + strandat 3892.372 kb on + strandat 3892.372 kb on + strandat 3892.414 kb on + strandat 3892.414 kb on + strandat 3892.414 kb on + strandat 3892.415 kb on - strandat 3892.415 kb on - strandat 3892.415 kb on - strandat 3892.415 kb on - strandat 3892.418 kb on + strandat 3892.447 kb on + strandat 3892.448 kb on - strandat 3892.517 kb on + strand, within Rv3476cat 3892.528 kb on + strand, within Rv3476cat 3892.720 kb on + strand, within Rv3476cat 3892.735 kb on + strand, within Rv3476cat 3892.736 kb on - strand, within Rv3476cat 3892.739 kb on + strand, within Rv3476cat 3892.741 kb on + strand, within Rv3476cat 3892.742 kb on - strand, within Rv3476cat 3892.742 kb on - strand, within Rv3476cat 3892.921 kb on + strand, within Rv3476cat 3892.922 kb on - strand, within Rv3476cat 3892.922 kb on - strand, within Rv3476cat 3892.926 kb on - strand, within Rv3476c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dibucaine 0.21 mM
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3,890,200 + Rv3473c 0.32 -0.2
3,890,201 - Rv3473c 0.32 -1.6
3,890,220 + Rv3473c 0.35 +0.7
3,890,221 - Rv3473c 0.35 -0.3
3,890,253 - Rv3473c 0.39 -0.2
3,890,253 - Rv3473c 0.39 -0.8
3,890,327 + Rv3473c 0.48 +0.0
3,890,327 + Rv3473c 0.48 +0.0
3,890,328 - Rv3473c 0.48 +0.2
3,892,223 + -0.0
3,892,223 + +0.5
3,892,224 - +1.3
3,892,356 - +0.6
3,892,356 - -0.3
3,892,372 + -0.4
3,892,372 + -0.9
3,892,372 + +0.3
3,892,372 + +0.3
3,892,414 + -0.3
3,892,414 + +1.7
3,892,414 + -0.5
3,892,415 - -0.2
3,892,415 - +1.4
3,892,415 - -0.0
3,892,415 - +0.0
3,892,418 + -0.5
3,892,447 + -2.0
3,892,448 - -2.4
3,892,517 + Rv3476c 0.11 +0.9
3,892,528 + Rv3476c 0.12 +0.8
3,892,720 + Rv3476c 0.26 -0.6
3,892,735 + Rv3476c 0.27 -0.6
3,892,736 - Rv3476c 0.27 +1.9
3,892,739 + Rv3476c 0.27 +1.9
3,892,741 + Rv3476c 0.27 -0.2
3,892,742 - Rv3476c 0.27 +1.4
3,892,742 - Rv3476c 0.27 +0.1
3,892,921 + Rv3476c 0.41 -0.5
3,892,922 - Rv3476c 0.41 +0.7
3,892,922 - Rv3476c 0.41 -0.4
3,892,926 - Rv3476c 0.41 -0.3

Or see this region's nucleotide sequence