Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2945c

Experiment: 7H9 with Dibucaine 0.21 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2943 and Rv2943A overlap by 1 nucleotidesRv2943A and Rv2944 overlap by 446 nucleotidesRv2944 and Rv2945c are separated by 117 nucleotidesRv2945c and Rv2946c are separated by 177 nucleotides Rv2943: Rv2943 - Probable transposase for insertion sequence element IS1533, at 3,288,464 to 3,289,705 Rv2943 Rv2943A: Rv2943A - Possible transposase, at 3,289,705 to 3,290,235 Rv2943A Rv2944: Rv2944 - Possible transposase for insertion sequence element IS1533, at 3,289,790 to 3,290,506 Rv2944 Rv2945c: Rv2945c - Probable conserved lipoprotein LppX, at 3,290,624 to 3,291,325 Rv2945c Rv2946c: Rv2946c - Probable polyketide synthase Pks1, at 3,291,503 to 3,296,353 Rv2946c Position (kb) 3290 3291 3292Strain fitness (log2 ratio) -2 -1 0 1at 3289.849 kb on + strandat 3290.831 kb on + strand, within Rv2945cat 3290.832 kb on - strand, within Rv2945cat 3290.832 kb on - strand, within Rv2945cat 3290.842 kb on + strand, within Rv2945cat 3290.987 kb on + strand, within Rv2945cat 3291.018 kb on + strand, within Rv2945cat 3291.018 kb on + strand, within Rv2945cat 3291.018 kb on + strand, within Rv2945cat 3291.019 kb on - strand, within Rv2945cat 3291.027 kb on - strand, within Rv2945cat 3291.076 kb on + strand, within Rv2945cat 3291.076 kb on + strand, within Rv2945cat 3291.076 kb on + strand, within Rv2945cat 3291.076 kb on + strand, within Rv2945cat 3291.076 kb on + strand, within Rv2945cat 3291.077 kb on - strand, within Rv2945cat 3291.119 kb on + strand, within Rv2945cat 3291.278 kb on + strandat 3291.278 kb on + strandat 3291.278 kb on + strandat 3291.278 kb on + strandat 3291.278 kb on + strandat 3291.279 kb on - strandat 3291.279 kb on - strandat 3291.279 kb on - strandat 3291.279 kb on - strandat 3291.279 kb on - strandat 3291.336 kb on + strandat 3291.337 kb on - strandat 3291.519 kb on - strandat 3291.519 kb on - strandat 3291.604 kb on - strandat 3291.806 kb on + strandat 3291.807 kb on - strandat 3291.968 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dibucaine 0.21 mM
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3,289,849 + -0.1
3,290,831 + Rv2945c 0.29 -1.5
3,290,832 - Rv2945c 0.30 -0.7
3,290,832 - Rv2945c 0.30 -1.2
3,290,842 + Rv2945c 0.31 -1.2
3,290,987 + Rv2945c 0.52 -1.3
3,291,018 + Rv2945c 0.56 -0.9
3,291,018 + Rv2945c 0.56 -1.0
3,291,018 + Rv2945c 0.56 -1.2
3,291,019 - Rv2945c 0.56 -1.6
3,291,027 - Rv2945c 0.57 -1.6
3,291,076 + Rv2945c 0.64 -0.5
3,291,076 + Rv2945c 0.64 -2.2
3,291,076 + Rv2945c 0.64 -1.8
3,291,076 + Rv2945c 0.64 -1.6
3,291,076 + Rv2945c 0.64 -1.0
3,291,077 - Rv2945c 0.65 -1.9
3,291,119 + Rv2945c 0.71 -0.6
3,291,278 + -1.0
3,291,278 + -1.1
3,291,278 + +0.1
3,291,278 + -1.1
3,291,278 + -0.8
3,291,279 - -1.6
3,291,279 - -0.8
3,291,279 - -0.2
3,291,279 - +0.1
3,291,279 - -1.1
3,291,336 + -0.6
3,291,337 - -1.5
3,291,519 - -0.8
3,291,519 - +1.1
3,291,604 - -0.2
3,291,806 + -0.6
3,291,807 - +0.4
3,291,968 + -1.3

Or see this region's nucleotide sequence