Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2702

Experiment: 7H9 with Dibucaine 0.21 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2701c and Rv2702 are separated by 122 nucleotidesRv2702 and Rv2703 are separated by 179 nucleotides Rv2701c: Rv2701c - Inositol-1-monophosphatase SuhB, at 3,015,863 to 3,016,735 Rv2701c Rv2702: Rv2702 - Polyphosphate glucokinase PpgK (polyphosphate-glucose phosphotransferase), at 3,016,858 to 3,017,655 Rv2702 Rv2703: Rv2703 - RNA polymerase sigma factor SigA (sigma-A), at 3,017,835 to 3,019,421 Rv2703 Position (kb) 3016 3017 3018Strain fitness (log2 ratio) -2 -1 0 1 2 3at 3015.899 kb on + strandat 3015.899 kb on + strandat 3016.056 kb on + strand, within Rv2701cat 3016.056 kb on + strand, within Rv2701cat 3016.057 kb on - strand, within Rv2701cat 3016.083 kb on - strand, within Rv2701cat 3016.302 kb on + strand, within Rv2701cat 3016.303 kb on - strand, within Rv2701cat 3016.396 kb on - strand, within Rv2701cat 3016.741 kb on + strandat 3016.742 kb on - strandat 3016.820 kb on + strandat 3016.820 kb on + strandat 3016.820 kb on + strandat 3017.098 kb on + strand, within Rv2702at 3017.579 kb on + strandat 3017.643 kb on + strandat 3017.643 kb on + strandat 3017.688 kb on + strandat 3017.694 kb on + strandat 3017.694 kb on + strandat 3017.694 kb on + strandat 3017.815 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dibucaine 0.21 mM
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3,015,899 + +0.2
3,015,899 + +0.5
3,016,056 + Rv2701c 0.22 -0.2
3,016,056 + Rv2701c 0.22 -0.5
3,016,057 - Rv2701c 0.22 -0.3
3,016,083 - Rv2701c 0.25 -0.0
3,016,302 + Rv2701c 0.50 -0.6
3,016,303 - Rv2701c 0.50 +1.8
3,016,396 - Rv2701c 0.61 -0.5
3,016,741 + -0.3
3,016,742 - -1.3
3,016,820 + +0.2
3,016,820 + +0.3
3,016,820 + +0.0
3,017,098 + Rv2702 0.30 -0.8
3,017,579 + -0.0
3,017,643 + -0.8
3,017,643 + -0.2
3,017,688 + -1.2
3,017,694 + +0.8
3,017,694 + +0.2
3,017,694 + +2.8
3,017,815 + -1.9

Or see this region's nucleotide sequence