Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2380c

Experiment: 7H9 with Dibucaine 0.21 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2379c and Rv2380c overlap by 19 nucleotidesRv2380c and Rv2381c are separated by 139 nucleotides Rv2379c: Rv2379c - Peptide synthetase MbtF (peptide synthase), at 2,657,700 to 2,662,085 Rv2379c Rv2380c: Rv2380c - Peptide synthetase MbtE (peptide synthase), at 2,662,067 to 2,667,115 Rv2380c Rv2381c: Rv2381c - Polyketide synthetase MbtD (polyketide synthase), at 2,667,255 to 2,670,269 Rv2381c Position (kb) 2662 2663 2664 2665 2666 2667 2668Strain fitness (log2 ratio) -2 -1 0 1 2 3at 2661.103 kb on - strand, within Rv2379cat 2661.103 kb on - strand, within Rv2379cat 2661.799 kb on - strandat 2661.832 kb on - strandat 2662.248 kb on - strandat 2662.643 kb on - strand, within Rv2380cat 2662.662 kb on + strand, within Rv2380cat 2662.827 kb on + strand, within Rv2380cat 2662.828 kb on - strand, within Rv2380cat 2662.828 kb on - strand, within Rv2380cat 2663.091 kb on + strand, within Rv2380cat 2663.091 kb on + strand, within Rv2380cat 2663.092 kb on - strand, within Rv2380cat 2663.092 kb on - strand, within Rv2380cat 2663.092 kb on - strand, within Rv2380cat 2663.092 kb on - strand, within Rv2380cat 2664.422 kb on - strand, within Rv2380cat 2664.423 kb on + strand, within Rv2380cat 2664.517 kb on - strand, within Rv2380cat 2665.306 kb on - strand, within Rv2380cat 2665.306 kb on - strand, within Rv2380cat 2665.570 kb on - strand, within Rv2380cat 2666.427 kb on + strand, within Rv2380cat 2667.254 kb on - strandat 2667.550 kb on + strandat 2667.705 kb on - strand, within Rv2381c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dibucaine 0.21 mM
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2,661,103 - Rv2379c 0.78 +1.2
2,661,103 - Rv2379c 0.78 -0.3
2,661,799 - -1.4
2,661,832 - +1.8
2,662,248 - -1.4
2,662,643 - Rv2380c 0.11 -1.1
2,662,662 + Rv2380c 0.12 -0.5
2,662,827 + Rv2380c 0.15 -0.0
2,662,828 - Rv2380c 0.15 -0.6
2,662,828 - Rv2380c 0.15 -0.3
2,663,091 + Rv2380c 0.20 -0.5
2,663,091 + Rv2380c 0.20 +0.8
2,663,092 - Rv2380c 0.20 -2.1
2,663,092 - Rv2380c 0.20 -0.5
2,663,092 - Rv2380c 0.20 -0.9
2,663,092 - Rv2380c 0.20 +0.4
2,664,422 - Rv2380c 0.47 -1.6
2,664,423 + Rv2380c 0.47 -0.2
2,664,517 - Rv2380c 0.49 +0.2
2,665,306 - Rv2380c 0.64 +2.8
2,665,306 - Rv2380c 0.64 -2.0
2,665,570 - Rv2380c 0.69 -1.2
2,666,427 + Rv2380c 0.86 -0.8
2,667,254 - -2.5
2,667,550 + -1.5
2,667,705 - Rv2381c 0.15 +0.2

Or see this region's nucleotide sequence