Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2366c

Experiment: 7H9 with Dibucaine 0.21 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2364c and Rv2365c are separated by 73 nucleotidesRv2365c and Rv2366c overlap by 29 nucleotidesRv2366c and Rv2367c overlap by 4 nucleotidesRv2367c and Rv2368c are separated by 3 nucleotides Rv2364c: Rv2364c - Probable GTP-binding protein Era, at 2,645,771 to 2,646,673 Rv2364c Rv2365c: Rv2365c - Conserved hypothetical protein, at 2,646,747 to 2,647,088 Rv2365c Rv2366c: Rv2366c - Probable conserved transmembrane protein, at 2,647,060 to 2,648,367 Rv2366c Rv2367c: Rv2367c - Conserved hypothetical protein, at 2,648,364 to 2,648,912 Rv2367c Rv2368c: Rv2368c - Probable PHOH-like protein PhoH1 (phosphate starvation-inducible protein PSIH), at 2,648,916 to 2,649,974 Rv2368c Position (kb) 2647 2648 2649Strain fitness (log2 ratio) -2 -1 0 1 2 3at 2646.953 kb on - strand, within Rv2365cat 2647.054 kb on - strandat 2647.287 kb on - strand, within Rv2366cat 2648.091 kb on - strand, within Rv2366cat 2648.091 kb on - strand, within Rv2366cat 2648.218 kb on - strand, within Rv2366cat 2648.255 kb on - strandat 2648.255 kb on - strandat 2648.255 kb on - strandat 2648.255 kb on - strandat 2648.255 kb on - strandat 2648.355 kb on - strandat 2648.355 kb on - strandat 2648.378 kb on - strandat 2648.378 kb on - strandat 2648.432 kb on - strand, within Rv2367cat 2648.432 kb on - strand, within Rv2367cat 2648.898 kb on - strandat 2648.898 kb on - strandat 2648.992 kb on + strandat 2649.257 kb on + strand, within Rv2368cat 2649.269 kb on - strand, within Rv2368cat 2649.353 kb on - strand, within Rv2368cat 2649.353 kb on - strand, within Rv2368cat 2649.363 kb on + strand, within Rv2368cat 2649.363 kb on + strand, within Rv2368cat 2649.364 kb on - strand, within Rv2368c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dibucaine 0.21 mM
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2,646,953 - Rv2365c 0.60 -0.3
2,647,054 - -1.4
2,647,287 - Rv2366c 0.17 -2.7
2,648,091 - Rv2366c 0.79 +0.4
2,648,091 - Rv2366c 0.79 -0.8
2,648,218 - Rv2366c 0.89 -0.4
2,648,255 - -0.3
2,648,255 - +0.2
2,648,255 - -0.0
2,648,255 - -0.6
2,648,255 - +2.8
2,648,355 - -0.9
2,648,355 - -0.4
2,648,378 - +1.8
2,648,378 - -0.8
2,648,432 - Rv2367c 0.12 -0.0
2,648,432 - Rv2367c 0.12 -1.2
2,648,898 - -0.7
2,648,898 - -1.2
2,648,992 + -0.1
2,649,257 + Rv2368c 0.32 -0.5
2,649,269 - Rv2368c 0.33 -1.0
2,649,353 - Rv2368c 0.41 +0.3
2,649,353 - Rv2368c 0.41 -1.4
2,649,363 + Rv2368c 0.42 -0.4
2,649,363 + Rv2368c 0.42 -0.0
2,649,364 - Rv2368c 0.42 -0.4

Or see this region's nucleotide sequence