Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1662

Experiment: 7H9 with Dibucaine 0.21 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1661 and Rv1662 are separated by 19 nucleotidesRv1662 and Rv1663 overlap by 1 nucleotides Rv1661: Rv1661 - Probable polyketide synthase Pks7, at 1,875,304 to 1,881,684 Rv1661 Rv1662: Rv1662 - Probable polyketide synthase Pks8, at 1,881,704 to 1,886,512 Rv1662 Rv1663: Rv1663 - Probable polyketide synthase Pks17, at 1,886,512 to 1,888,020 Rv1663 Position (kb) 1881 1882 1883 1884 1885 1886 1887Strain fitness (log2 ratio) -1 0 1 2at 1880.993 kb on + strand, within Rv1661at 1882.045 kb on + strandat 1883.437 kb on - strand, within Rv1662at 1884.257 kb on - strand, within Rv1662at 1884.705 kb on + strand, within Rv1662at 1885.426 kb on + strand, within Rv1662at 1887.416 kb on + strand, within Rv1663

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dibucaine 0.21 mM
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1,880,993 + Rv1661 0.89 +0.2
1,882,045 + -0.2
1,883,437 - Rv1662 0.36 -0.9
1,884,257 - Rv1662 0.53 -0.8
1,884,705 + Rv1662 0.62 -0.9
1,885,426 + Rv1662 0.77 +1.8
1,887,416 + Rv1663 0.60 -0.3

Or see this region's nucleotide sequence