Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1329c

Experiment: 7H9 with Dibucaine 0.21 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1328 and Rv1329c are separated by 39 nucleotidesRv1329c and Rv1330c are separated by 23 nucleotides Rv1328: Rv1328 - Probable glycogen phosphorylase GlgP, at 1,494,564 to 1,497,155 Rv1328 Rv1329c: Rv1329c - Probable ATP-dependent helicase DinG, at 1,497,195 to 1,499,189 Rv1329c Rv1330c: Rv1330c - Nicotinic acid phosphoribosyltransferase PncB1, at 1,499,213 to 1,500,559 Rv1330c Position (kb) 1497 1498 1499 1500Strain fitness (log2 ratio) -2 -1 0 1 2 3at 1496.319 kb on + strand, within Rv1328at 1496.598 kb on + strand, within Rv1328at 1496.652 kb on - strand, within Rv1328at 1496.657 kb on - strand, within Rv1328at 1496.657 kb on - strand, within Rv1328at 1496.657 kb on - strand, within Rv1328at 1496.716 kb on - strand, within Rv1328at 1496.719 kb on - strand, within Rv1328at 1496.791 kb on - strand, within Rv1328at 1496.861 kb on + strand, within Rv1328at 1496.978 kb on - strandat 1497.082 kb on - strandat 1498.144 kb on - strand, within Rv1329cat 1498.243 kb on + strand, within Rv1329cat 1498.244 kb on - strand, within Rv1329cat 1498.382 kb on + strand, within Rv1329cat 1498.670 kb on + strand, within Rv1329cat 1498.670 kb on + strand, within Rv1329cat 1498.670 kb on + strand, within Rv1329cat 1498.670 kb on + strand, within Rv1329cat 1498.671 kb on - strand, within Rv1329cat 1499.015 kb on - strandat 1499.493 kb on + strand, within Rv1330cat 1499.494 kb on - strand, within Rv1330cat 1499.494 kb on - strand, within Rv1330cat 1499.516 kb on + strand, within Rv1330cat 1499.525 kb on + strand, within Rv1330cat 1499.541 kb on + strand, within Rv1330cat 1499.542 kb on - strand, within Rv1330cat 1499.599 kb on - strand, within Rv1330cat 1499.599 kb on - strand, within Rv1330cat 1499.684 kb on + strand, within Rv1330cat 1499.808 kb on + strand, within Rv1330cat 1499.808 kb on + strand, within Rv1330cat 1499.809 kb on - strand, within Rv1330cat 1499.812 kb on + strand, within Rv1330cat 1499.813 kb on - strand, within Rv1330cat 1499.813 kb on - strand, within Rv1330cat 1499.813 kb on - strand, within Rv1330cat 1500.003 kb on + strand, within Rv1330cat 1500.003 kb on + strand, within Rv1330c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dibucaine 0.21 mM
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1,496,319 + Rv1328 0.68 +2.8
1,496,598 + Rv1328 0.78 -0.5
1,496,652 - Rv1328 0.81 -1.2
1,496,657 - Rv1328 0.81 +0.4
1,496,657 - Rv1328 0.81 -0.1
1,496,657 - Rv1328 0.81 +0.1
1,496,716 - Rv1328 0.83 -1.0
1,496,719 - Rv1328 0.83 +0.1
1,496,791 - Rv1328 0.86 -1.8
1,496,861 + Rv1328 0.89 +0.2
1,496,978 - -0.0
1,497,082 - +0.8
1,498,144 - Rv1329c 0.48 +0.1
1,498,243 + Rv1329c 0.53 -0.6
1,498,244 - Rv1329c 0.53 -0.2
1,498,382 + Rv1329c 0.59 -2.5
1,498,670 + Rv1329c 0.74 -1.6
1,498,670 + Rv1329c 0.74 -1.0
1,498,670 + Rv1329c 0.74 -1.3
1,498,670 + Rv1329c 0.74 -0.3
1,498,671 - Rv1329c 0.74 -1.0
1,499,015 - -0.9
1,499,493 + Rv1330c 0.21 -0.7
1,499,494 - Rv1330c 0.21 -0.6
1,499,494 - Rv1330c 0.21 -0.7
1,499,516 + Rv1330c 0.22 -0.1
1,499,525 + Rv1330c 0.23 -0.1
1,499,541 + Rv1330c 0.24 -0.4
1,499,542 - Rv1330c 0.24 -1.0
1,499,599 - Rv1330c 0.29 -0.4
1,499,599 - Rv1330c 0.29 +0.4
1,499,684 + Rv1330c 0.35 -0.5
1,499,808 + Rv1330c 0.44 +1.8
1,499,808 + Rv1330c 0.44 +1.8
1,499,809 - Rv1330c 0.44 +0.1
1,499,812 + Rv1330c 0.44 -0.4
1,499,813 - Rv1330c 0.45 +0.8
1,499,813 - Rv1330c 0.45 +0.8
1,499,813 - Rv1330c 0.45 -0.1
1,500,003 + Rv1330c 0.59 -0.6
1,500,003 + Rv1330c 0.59 -1.5

Or see this region's nucleotide sequence