Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1131

Experiment: 7H9 with Dibucaine 0.21 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1130 and Rv1131 overlap by 4 nucleotidesRv1131 and Rv1132 are separated by 11 nucleotides Rv1130: Rv1130 - Possible methylcitrate dehydratase PrpD, at 1,254,555 to 1,256,135 Rv1130 Rv1131: Rv1131 - Probable methylcitrate synthase PrpC, at 1,256,132 to 1,257,313 Rv1131 Rv1132: Rv1132 - Conserved membrane protein, at 1,257,325 to 1,259,055 Rv1132 Position (kb) 1256 1257 1258Strain fitness (log2 ratio) -1 0 1 2at 1255.198 kb on - strand, within Rv1130at 1255.467 kb on + strand, within Rv1130at 1255.598 kb on - strand, within Rv1130at 1255.598 kb on - strand, within Rv1130at 1255.678 kb on - strand, within Rv1130at 1256.810 kb on + strand, within Rv1131at 1256.811 kb on - strand, within Rv1131at 1257.072 kb on - strand, within Rv1131at 1257.199 kb on + strandat 1257.273 kb on - strandat 1257.312 kb on - strandat 1257.317 kb on + strandat 1257.615 kb on - strand, within Rv1132at 1258.001 kb on + strand, within Rv1132at 1258.002 kb on - strand, within Rv1132at 1258.002 kb on - strand, within Rv1132

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dibucaine 0.21 mM
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1,255,198 - Rv1130 0.41 +1.9
1,255,467 + Rv1130 0.58 -0.2
1,255,598 - Rv1130 0.66 +0.7
1,255,598 - Rv1130 0.66 +0.8
1,255,678 - Rv1130 0.71 -0.3
1,256,810 + Rv1131 0.57 -1.2
1,256,811 - Rv1131 0.57 -0.6
1,257,072 - Rv1131 0.80 -1.1
1,257,199 + -0.3
1,257,273 - -0.2
1,257,312 - -0.1
1,257,317 + -0.7
1,257,615 - Rv1132 0.17 -0.0
1,258,001 + Rv1132 0.39 +0.0
1,258,002 - Rv1132 0.39 -0.6
1,258,002 - Rv1132 0.39 +0.1

Or see this region's nucleotide sequence