Experiment: 7H9 with Dibucaine 0.21 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0938 and Rv0939 overlap by 4 nucleotides Rv0939 and Rv0940c are separated by 246 nucleotides
Rv0938: Rv0938 - ATP dependent DNA ligase LigD (ATP dependent polydeoxyribonucleotide synthase) (thermostable DNA ligase) (ATP dependent polynucleotide ligase) (sealase) (DNA repair enzyme) (DNA joinase), at 1,046,136 to 1,048,415
Rv0938
Rv0939: Rv0939 - Possible bifunctional enzyme: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase) + cyclase/dehydrase, at 1,048,412 to 1,050,346
Rv0939
Rv0940c: Rv0940c - Possible oxidoreductase, at 1,050,593 to 1,051,459
Rv0940c
Position (kb) 1048
1049
1050
1051 Strain fitness (log2 ratio) -2
-1
0
1
2 at 1048.005 kb on + strand, within Rv0938 at 1048.255 kb on + strand at 1048.290 kb on + strand at 1048.291 kb on - strand at 1048.479 kb on - strand at 1049.136 kb on - strand, within Rv0939 at 1049.525 kb on - strand, within Rv0939 at 1050.248 kb on + strand at 1050.248 kb on + strand at 1051.318 kb on - strand, within Rv0940c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Dibucaine 0.21 mM remove 1,048,005 + Rv0938 0.82 -0.2 1,048,255 + -0.6 1,048,290 + -0.3 1,048,291 - -0.4 1,048,479 - -0.6 1,049,136 - Rv0939 0.37 +1.9 1,049,525 - Rv0939 0.58 -1.6 1,050,248 + +0.1 1,050,248 + -1.9 1,051,318 - Rv0940c 0.84 -0.2
Or see this region's nucleotide sequence