Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0395

Experiment: 7H9 with Dibucaine 0.21 mM

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv0393 and Rv0394c are separated by 15 nucleotidesRv0394c and Rv0395 are separated by 98 nucleotidesRv0395 and Rv0396 are separated by 5 nucleotidesRv0396 and Rv0397 are separated by 73 nucleotides Rv0393: Rv0393 - Conserved 13E12 repeat family protein, at 472,781 to 474,106 Rv0393 Rv0394c: Rv0394c - Possible secreted protein, at 474,122 to 474,841 Rv0394c Rv0395: Rv0395 - Hypothetical protein, at 474,940 to 475,344 Rv0395 Rv0396: Rv0396 - Hypothetical protein, at 475,350 to 475,742 Rv0396 Rv0397: Rv0397 - Conserved 13E12 repeat family protein, at 475,816 to 476,184 Rv0397 Position (kb) 474 475 476Strain fitness (log2 ratio) -3 -2 -1 0 1at 474.225 kb on + strand, within Rv0394cat 474.226 kb on - strand, within Rv0394cat 474.386 kb on - strand, within Rv0394cat 474.476 kb on - strand, within Rv0394cat 474.593 kb on - strand, within Rv0394cat 474.698 kb on + strand, within Rv0394cat 474.841 kb on + strandat 474.854 kb on - strandat 474.854 kb on - strandat 474.854 kb on - strandat 474.854 kb on - strandat 475.140 kb on + strand, within Rv0395at 475.227 kb on + strand, within Rv0395at 475.260 kb on - strand, within Rv0395at 475.326 kb on - strandat 475.326 kb on - strandat 475.342 kb on + strandat 475.343 kb on - strandat 475.343 kb on - strandat 475.369 kb on + strandat 475.438 kb on - strand, within Rv0396at 475.438 kb on - strand, within Rv0396at 475.898 kb on - strand, within Rv0397at 475.898 kb on - strand, within Rv0397at 475.898 kb on - strand, within Rv0397at 476.183 kb on - strandat 476.314 kb on + strandat 476.315 kb on - strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dibucaine 0.21 mM
remove
474,225 + Rv0394c 0.14 +0.2
474,226 - Rv0394c 0.14 -0.5
474,386 - Rv0394c 0.37 +0.8
474,476 - Rv0394c 0.49 +1.1
474,593 - Rv0394c 0.65 +0.5
474,698 + Rv0394c 0.80 -0.2
474,841 + -0.2
474,854 - +0.1
474,854 - +0.1
474,854 - -0.3
474,854 - -0.3
475,140 + Rv0395 0.49 -1.8
475,227 + Rv0395 0.71 -0.5
475,260 - Rv0395 0.79 -1.6
475,326 - +0.6
475,326 - +0.4
475,342 + +0.4
475,343 - +0.3
475,343 - -0.7
475,369 + +0.0
475,438 - Rv0396 0.22 -3.5
475,438 - Rv0396 0.22 -0.4
475,898 - Rv0397 0.22 +0.1
475,898 - Rv0397 0.22 +0.1
475,898 - Rv0397 0.22 -0.5
476,183 - +0.9
476,314 + -0.9
476,315 - +0.8

Or see this region's nucleotide sequence