Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1168c

Experiment: 7H9 with Phenazine methosulfate 0.0054 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1166 and Rv1167c are separated by 27 nucleotidesRv1167c and Rv1168c are separated by 71 nucleotidesRv1168c and Rv1169c are separated by 17 nucleotidesRv1169c and Rv1170 are separated by 179 nucleotides Rv1166: Rv1166 - Probable conserved lipoprotein LpqW, at 1,296,152 to 1,298,059 Rv1166 Rv1167c: Rv1167c - Probable transcriptional regulatory protein, at 1,298,087 to 1,298,692 Rv1167c Rv1168c: Rv1168c - PPE family protein PPE17, at 1,298,764 to 1,299,804 Rv1168c Rv1169c: Rv1169c - PE family protein. Possible lipase LipX., at 1,299,822 to 1,300,124 Rv1169c Rv1170: Rv1170 - N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase), at 1,300,304 to 1,301,215 Rv1170 Position (kb) 1298 1299 1300Strain fitness (log2 ratio) -1 0 1 2 3at 1298.057 kb on + strandat 1298.058 kb on - strandat 1298.089 kb on - strandat 1298.342 kb on + strand, within Rv1167cat 1298.527 kb on - strand, within Rv1167cat 1298.622 kb on + strand, within Rv1167cat 1298.704 kb on - strandat 1298.704 kb on - strandat 1298.788 kb on + strandat 1298.922 kb on + strand, within Rv1168cat 1298.923 kb on - strand, within Rv1168cat 1299.022 kb on + strand, within Rv1168cat 1299.122 kb on + strand, within Rv1168cat 1299.122 kb on + strand, within Rv1168cat 1299.122 kb on + strand, within Rv1168cat 1299.123 kb on - strand, within Rv1168cat 1299.123 kb on - strand, within Rv1168cat 1299.266 kb on + strand, within Rv1168cat 1299.266 kb on + strand, within Rv1168cat 1299.267 kb on - strand, within Rv1168cat 1299.353 kb on + strand, within Rv1168cat 1299.387 kb on - strand, within Rv1168cat 1299.395 kb on + strand, within Rv1168cat 1299.396 kb on - strand, within Rv1168cat 1299.692 kb on + strand, within Rv1168cat 1299.736 kb on + strandat 1299.737 kb on - strandat 1299.866 kb on - strand, within Rv1169cat 1299.940 kb on + strand, within Rv1169cat 1299.941 kb on - strand, within Rv1169cat 1299.941 kb on - strand, within Rv1169cat 1300.231 kb on - strandat 1300.293 kb on - strandat 1300.385 kb on + strandat 1300.385 kb on + strandat 1300.386 kb on - strandat 1300.503 kb on - strand, within Rv1170at 1300.709 kb on + strand, within Rv1170at 1300.710 kb on - strand, within Rv1170at 1300.728 kb on - strand, within Rv1170

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Phenazine methosulfate 0.0054 mM
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1,298,057 + -0.2
1,298,058 - -0.5
1,298,089 - +0.1
1,298,342 + Rv1167c 0.42 -1.5
1,298,527 - Rv1167c 0.73 +2.9
1,298,622 + Rv1167c 0.88 +0.1
1,298,704 - -0.0
1,298,704 - -0.3
1,298,788 + -0.2
1,298,922 + Rv1168c 0.15 +0.6
1,298,923 - Rv1168c 0.15 +0.5
1,299,022 + Rv1168c 0.25 -1.7
1,299,122 + Rv1168c 0.34 -0.7
1,299,122 + Rv1168c 0.34 -0.2
1,299,122 + Rv1168c 0.34 +0.0
1,299,123 - Rv1168c 0.34 -0.1
1,299,123 - Rv1168c 0.34 +0.7
1,299,266 + Rv1168c 0.48 +0.3
1,299,266 + Rv1168c 0.48 +2.5
1,299,267 - Rv1168c 0.48 -0.4
1,299,353 + Rv1168c 0.57 +0.1
1,299,387 - Rv1168c 0.60 +0.5
1,299,395 + Rv1168c 0.61 +0.8
1,299,396 - Rv1168c 0.61 +0.2
1,299,692 + Rv1168c 0.89 -0.1
1,299,736 + -0.3
1,299,737 - +1.3
1,299,866 - Rv1169c 0.15 +2.9
1,299,940 + Rv1169c 0.39 -0.2
1,299,941 - Rv1169c 0.39 +0.9
1,299,941 - Rv1169c 0.39 -0.7
1,300,231 - -0.1
1,300,293 - -0.3
1,300,385 + -1.6
1,300,385 + +0.3
1,300,386 - +0.1
1,300,503 - Rv1170 0.22 -0.0
1,300,709 + Rv1170 0.44 -0.9
1,300,710 - Rv1170 0.45 -1.5
1,300,728 - Rv1170 0.46 +0.7

Or see this region's nucleotide sequence